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Development and implementation of ontology-based systems for mammalian gene expression profiling
(2009)
The use of ontologies in the mapping of gene expression events provides an
effective and comparable method to determine the expression profile of an entire
genome across a large collection of experiments derived from ...
Generation of a human gene index and its application to disease candidacy
(University of the Western Cape, 2001)
With easy access to technology to generate expressed sequence tags (ESTs), several groups have sequenced from thousands to several thousands of ESTs. These ESTs benefit from consolidation and organization to deliver ...
Concept Based Knowledge Discovery from Biomedical Literature
(University of the Western Cape, 2009)
This thesis describes and introduces novel methods for knowledge discovery and presents a software system that is able to extract information from biomedical literature, review interesting connections between various ...
Detection of positive selection resulting from Nevirapine treatment in longitudinal HIV-1 reverse transcriptase sequences
(University of the Western Cape, 2006)
Nevirapine (NVP) is a cheap anti-retroviral drug used in poor countries worldwide, administered to pregnant women at the onset of labour to inhibit HIV enzyme reverse transcriptase. Viruses which may get transmitted to ...
Computational analyses on transcriptional regulation in mammals
(University of the Western Cape, 2009)
The genomes of various organisms have been sequenced and their transcriptome elucidated. With the information about genes and gene products readily available it has become of the utmost importance to decipher the underlying ...
"Development and implementation of ontology-based systems for mammalian gene expression profiling"
(University of the Western Cape, 2009)
The use of ontologies in the mapping of gene expression events provides an effective and comparable method to determine the expression profile of an entire genome across a large collection of experiments derived from ...
Concept Based Knowledge Discovery From Biomedical Literature
(University of the Western Cape, 2009)
Advancement in biomedical research and continuous growth of scientific literature available in electronic form, calls for innovative methods and tools for information management, knowledge discovery, and data integration. ...