Browsing Department of Chemistry by Subject "Biosensor"
Now showing items 1-11 of 11
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Cytochrome P450-3A4/copper-poly(propylene imine)- polypyrrole star co-polymer Nanobiosensor system for delavirdine – a non-nucleoside reverse transcriptase inhibitor HIV drug
(University of the Western Cape, 2014)HIV and AIDS are among the world's pandemics that pose serious concern to almost every individual in the world. With the current level of availability of anti-retroviral (ARV) drugs and the ease of accessibility of treatment ... -
Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs
(University of Western Cape, 2020)Tuberculosis (TB) remains a global epidemic despite the fact that treatment has been available since the 1950’s. This disease is highly contagious and spreads via transmission of the Mycobacterium Tuberculosis (MTB) tubercle ... -
Electrochemical immunosensor based on cyclodextrin supramolecular interactions for the detection of human chorionic gonadotropin
(University of the Western Cape, 2012)Glucose oxidase (GOx) and horseradish peroxidase (HRP) are important enzymes for the development of amperometric enzyme linked immunosensors. The selectivity of each enzyme towards its analyte deepens its importance in ... -
Electrochemical Immunosensor based on Cyclodextrin Supramolecular interactions for the detection of human chorionic gonadotropin
(University of the Western Cape, 2012)Glucose oxidase (GOx) and horseradish peroxidase (HRP) are important enzymes for the development of amperometric enzyme linked immunosensors. The selectivity of each enzyme towards its analyte deepens its importance in ... -
Electrochemical impedance modelling of the reactivities of dendrimeric poly(propylene imine) DNA nanobiosensors
(University of the Western Cape, 2008)In this thesis, I present the electrochemical studies of three dendrimeric polypropylene imine (PPI) nanomaterials and their applications as a platform in the development of a novel label free DNA nanobiosensor based on ... -
Indium nanoparticulate-modified polyanilino-co-4-aminobenzoic acid amperometric sensor for the detection of lapatinib, a breast cancer drug.
(University of the Western Cape, 2022)Lapatinib is a highly prescribed drug used in combination with other drugs to treat breast cancer. Due to drug toxicity-related side effects experienced by some patients, there is need to determine appropriate dosage for ... -
Nanocomposite immunosensor for anti-transglutaminase antibody
(University of the Western Cape, 2009)Coeliac disease (CD) is a gluten intolerance condition that results in the flattening of the villi, which line the bowel. It is the most common cause of malabsorption of food nutrients. This inability to absorb sufficient ... -
Overoxidized polypyrrole-osmium telluride quantum dots immunosensor for prostate specific antigen – A cancer biomarker.
(University of the Western Cape, 2014)Prostate cancer is a deadly disease that occurs in the male’s prostate gland. A prostate gland is a walnut structure that forms part of the male’s reproductive system. Prostate cancer is caused by high level than normal ... -
Polyamic acid composites for multiiple sensing applications in complex sample matrices
(2013)Polyamic acid-polypyrrole (PAA/PPy) composite films were prepared and characterised for the use as conducting platforms in the design of biosensor systems. The thin films were synthesised by electrochemical method from a ... -
Polymeric tyrosinase nanobiosensor system for the determination of endocrine disrupting bisphenol A
(University of the Western Cape, 2011)The main objective of this work was to develop simple and sensitive electrochemical sensors for the detection of bisphenol A. To investigate the electrochemical behavior of BPA on a bare glassy carbon electrode. To apply ... -
Synthesis, electrodynamics and biosensor applications of novel sulphonated polyaniline nanocomposites
(University of the Western Cape, 2007)The overall aim of this thesis was to prepare nanostructured more processable heteronuclear sulphonated polyanyline nanocomposites with electroconductive properties suitable for applications in biosensors. The sulphonated ...