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Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease that, despite all efforts devoted towards its
eradication, remains a threat to many countries including South Africa. Current diagnostic
assays do offer better performance than ...
The development of graphene oxide sheet- and polyanilino-immunosensor systems for lipoarabinomannan (LAM) tuberculosis biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease with adverse effect on a global scale. The disease is one of the major causes of death in sub-Saharan Africa. Nearly 70% of TB-infected persons are co-infected by the human ...
Nanoparticulate of silver-modified poly (8-anilino-1-naphthalene sulphonic acid) nanobiosensor systems for the determination of Tuberculosis treatment drugs
(University of the Western Cape, 2011)
This study firstly reports the development and characterization of PVP-AgNPs, PANSA and PVPAgNPs/ PANSA nanocomposite on gold. AFM and TEM analyses revealed highly electroactive nanocomposites whose morphogy and properties ...
The synthesis and evaluation of potential anti-Mycobacterium tuberculosis and apoptotic agents
(University of the Western Cape, 2007)
Tuberculosis (TB) and Cancer are among the most devastating and therapeutically challenging diseases that need to be addressed in South Africa today. The development of muti-drug resistance in TB causing bacteria, Mycobacterium ...
Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs
(University of Western Cape, 2020)
Tuberculosis (TB) remains a global epidemic despite the fact that treatment has been available since the 1950’s. This disease is highly contagious and spreads via transmission of the Mycobacterium Tuberculosis (MTB) tubercle ...
Spectroelectrochemical graphene-silver/zinc oxide nanoparticulate phenotype biosensors for ethambutol and pyrazinamide
(University of the Western Cape, 2019)
Tuberculosis (TB), a deadly disease second to HIV/AIDS, is a global health problem.
Diagnosis of active tuberculosis is tedious and requires expensive procedures since there is
no recognizable method for sole detection ...
Graphenated organic nanoparticles immunosensors for the detection of TB biomarkers
(University of the Western Cape, 2017)
Pulmonary Tuberculosis (TB) a disease second to HIV/AIDS is a global health problem that
arises in two states; as an active state and as a latent state. Diagnosis of active TB is tedious
and requires expensive procedures ...
Gold nanoparticulate modified thioglycolic acid (tga) phenotype nanobiosensor for tuberculosis drugs
(University of the Western Cape, 2022)
Tuberculosis (TB) carries on being a major global health issue and it is responsible for 1.5 million disease-related mortality in 2020, according to the World Health organisation (WHO). One of the major causes of death ...
Carbon dot – polythionine nanocomposite sensor for the remediation of antibiotics in water
(University of the Western Cape, 2022)
Antibiotics are a necessary part of the world today where their main purpose is to
counter bacteria and diseases. Antibiotics are used in many areas which include
apiculture, domestic, livestock and medically. Since ...
Organometallic improvement of some tuberculosis drugs
(University of the Western Cape, 2023)
Metal-based drugs are preferred motifs that serve as major pharmacophores in bioactive
compounds for a variety of diseases, including as tuberculosis (TB). Heterocyclic, Schiff bases,
aliphatic amines and other ligands ...