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Quantum dots-amplified electrochemical cytochrome P450 phenotype sensor for tamoxifen, a breast cancer drug
(University of the Western Cape, 2017)
Breast cancer is regarded as the most common cancer in South Africa and its rate of
occurrence is increasing. About one in every 31 South African women are at the risk of
developing breast cancer and early diagnosis and ...
Cytochrome P450-3A4/copper-poly(propylene imine)- polypyrrole star co-polymer Nanobiosensor system for delavirdine – a non-nucleoside reverse transcriptase inhibitor HIV drug
(University of the Western Cape, 2014)
HIV and AIDS are among the world's pandemics that pose serious concern to almost every individual in the world. With the current level of availability of anti-retroviral (ARV) drugs and the ease of accessibility of treatment ...
Development of electrochemical sensors containing bimerallic silver and gold nanoparticles
(University of the Western Cape, 2010)
Polyaromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants that have been shown to be teratogenic, mutagenic and carcinogenic and pose serious threats to the health of aquatic and human life. Several methods ...
Development of electrochemical ZnSe Quantam dots biosensors for low-level detection of 17β-Estradiol estrogenic endocrine disrupting compound
(University of the Western Cape, 2010)
The main thesis hub was on development of two electrochemical biosensors for the determination of 17β-estradiol-estradiol: an estrogenic endocrine disrupting compound. Endocronology have significantly shown that the endocrine ...
Construction of an enzyme-free electrochemical sensor based on Ag-Fe2O3/POM/RGO novel nanocomposite for hydrogen peroxide detection
(University of the Western Cape, 2018)
The motivation to determine H2O2 lies in the fact that this chemical species plays a crucial role in diverse fields of practise such as cosmetic, food, diagnostic, pharmaceutical, clinical and environmental protection ...
Cytochrome C biosensor for the determination of trace level arsenic and cyanide compounds
(University of the Western Cape, 2011)
In this work, an electrochemical method based on a cyt c biosensor has been developed, for the detection of selected arsenic and cyanide compounds. Boron Doped Diamond (BDD) electrode was used as a transducer, onto which ...
Electrochemiluminescence of novel polyanilino-rutheniumbipyridyl-imidazo phenanthroline and carboxy-difluoroboradiazaindacene luminophores
(University of the Western Cape, 2015)
Electrochemiluminiscence, (ECL), is an electrochemically-induced process that leads to the generation of measurable luminescent signals at the electrode surface. The luminescent signals occur when electrochemically generated ...