A Study on Leadership in the Implementation of Non-Custodial Sentencing by the Department of Justice and Constitutional Development and the Department of Correctional Services
Abstract
In this study, new solid supramolecular derivatised forms of bis(adamantine-1-aminium)
carbonate (ADTCO3) were prepared. ADTCO3 is a derivative of amantadine used for
Parkinson’s disease and has antiviral properties against influenza-A, dengue fever and
pharmacological activity towards Parkinson’s disease. The new forms prepared were
polymorphic and co-crystal forms of ADTCO3. Polymorphism is a phenomenon where the
ability of a substance to exist in two or more crystalline forms occurs when crystallised
under different conditions and co-crystallization is the process of formation of
multicomponent crystals of a drug substance.