Browsing Faculty of Natural Science by Title
Now showing items 1005-1024 of 2565
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Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability
(University of the Western Cape, 2016)Background: Zidovudine (AZT) is a very useful drug for the management of Human Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. ... -
The formulation of a microsphere based fixed dose combination for oral antiretroviral delivery
(University of the Western Cape, 2023)The cost of providing antiretroviral therapy (ART) remains a significant economic burden on African countries due to poverty and a lack of resources. To reduce the economic burden of HIV infection, a formulation scientist ... -
Formulation of a nevirapine co-crystal as a liquid dosage form
(University of the Western Cape, 2016)Co-crystals are a solid phase phenomena that could enhance the physicochemical properties of an active pharmaceutical ingredient. A co-crystal has never been incorporated into a liquid dosage form with the assurance of ... -
The formulation, manufacture and evaluation of capsules containing freeze-dried aqueous extracts of Leonotis Leonorus or Mentha Longifolia
(University of the Western Cape, 2006)Leonotis leonorus and Mentha longifolia are two herbs commonly used in South Africa, mostly in oral liquid dosage forms. Several disadvantages are associated with these traditional dosage forms which can perhaps be remedied ... -
Fostering collaboration amongst business intelligence, business decision makers and statisticians for the optimal use of big data in marketing strategies
(University of the Western Cape, 2019)The aim of this study was to propose a model of collaboration adaptable for the optimal use of big data in an organisational environment. There is a paucity of knowledge on such collaboration and the research addressed ... -
Fractional Black-Scholes equations and their robust numerical simulations
(University of Western Cape, 2020)Conventional partial differential equations under the classical Black-Scholes approach have been extensively explored over the past few decades in solving option pricing problems. However, the underlying Efficient Market ... -
Fractional black-scholes equations and their robust numerical simulations
(University of the Western Cape, 2020)Conventional partial differential equations under the classical Black-Scholes approach have been extensively explored over the past few decades in solving option pricing problems. However, the underlying Efficient Market ... -
A framework for evaluating an introductory statistics programme at the University of the Western Cape
(University of the Western Cape, 2009)There have been calls both from the government and private sector for Higher Education institutions to introduce programmes that produce employable graduates whilst at the same time contributing to the growing economy of ... -
A framework for the analysis of discrete irregular patterned sequential datasets
(University of the Western Cape, 2023)Trial-and-error is often used for developing new deep learning models. There is no systematic procedure for improving existing models for predicting irregular sequential time-series. This research developed a systematic ... -
The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
(University of the Western Cape, 2014)The aim of the study was to detect the prevalence of AV and its associated bacteria with preterm delivery in the Western Cape, South Africa. Furthermore, it sought particularly to examine and investigate the predictive ... -
Frequency and voltage-modulated electrochemical aflatoxin B1 immunosensor systems prepared on electroactive organic polymer platforms
(University of the Western Cape, 2008)In the presented work, immunosensors for detection of Aflatoxin B1 based on different immobilization platforms were studied. Synthesis of an electroactive hydrogel was also carried out. Aflatoxins are a group of mycotoxins ... -
Frequency and voltage-modulated electrochemical aflatoxin b1immunosensor systems prepared on electroactive organic polymer platforms
(2008)In the presented work, immunosensors for detection of Aflatoxin B1 based on different immobilization platforms were studied. Synthesis of an electroactive hydrogel was also carried out. Aflatoxins are a group of mycotoxins ... -
From water resources management to integrated water resources management: an analysis of the establishment of new water management organisations in Namibia
(University of the Western Cape, 2010)The questions posed in this study address the different processes that were involved in the decision-making and establishment of the water management organisations, the extent of public participation, as well as features ... -
Functional analysis of miRNA regulated genes in prostate cancer as potential diagnostic molecules
(University of the Western Cape, 2016)Prostate Cancer is the leading cause of cancer-related death in males in the Western world. It is a common biological disease originating from the reproductive system of the male namely, the prostate gland, usually in older ... -
Functional analysis of the mouse RBBP6 gene using Interference RNA
(University of the Western Cape, 2007)The aim of this thesis was to investigate the cellular role of the mouse RBBP6 gene using the interference RNA (RNAi) gene targeting technology and also to understand the relevance of two promoters for the RBBP6 gene. -
Functional characterisation of a novel ferulic acid esterase from malawian hot spring metagenome
(2011)There has been a decline in the global fossil fuel reserves, due to an increasing demand for petroleum. Biofuels can be used as an alternative source of energy whereby biomass is converted to liquid fuels such as bioethanol. ... -
Functional characterisation of a thermophilic cellulase from a Malawian metagenomic library
(2013)Biofuels are currently recognised as the most viable source of energy to replace depleting fossil fuel reserves, with bioethanol the most popular alternative alcohol fuel. Producing bioethanol from agricultural waste ... -
Functional genomic characterization of fruit quality traits in apple (Malus x domestica Borkh)
(University of the Western Cape, 2009)The domesticated apple (Malus x domestica Borkh), belonging to the Malusgenus of the Rosaceae family, is one of the edible pomaceous fruits. Since it is one of the important commercial fruit crops worldwide, the quality ... -
Functional importance of snakes in a strandveld ecosystem
(University of the Western Cape, 2018)Gaps in our knowledge of the functional roles of snakes within ecosystems limit our ability to predict the potentially cascading effects their removal from an ecosystem might create. Extirpation of snake species could ... -
Functionalisation of electrospun nanofibre for lanthanide ion adsorption from aqueous solution
(University of the Western Cape, 2018)Rare earth elements (REEs) have widespread use and importance for industrial applications due to their metallurgical, optical and electronic properties. Several typical hydrometallurgical techniques such as adsorption, ...