Browsing Faculty of Natural Science by Title
Now showing items 487-506 of 2566
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Design of a thermoresponsive hydrogel for enhanced intratumoral permeation of a chemotherapeutic agent in oral squamous cell carcinoma
(University of the Western Cape, 2023)Introduction: Oral squamous cell carcinoma is the most common and aggressive cancer occurring in the oral cavity. Intravenous chemotherapy remains a pivotal part of treatment for the disease; however, these drugs cause ... -
The design of ultrasensitive immunosensors based on a new multi-signal amplification gold nanoparticles-dotted 4-nitrophenylazo functionalised graphene sensing platform for the determination of deoxynivalenol
(University of Western Cape, 2014)A highly dispersive gold nanoparticle-dotted 4-nitrophenylazo functionalised graphene nanocomposite (AuNp/G/PhNO2) was successfully synthesised and applied in enhancing sensing platform signals. Three label-free ... -
Design, analysis and simulation of a robust numerical method to solve Zika virus models
(University of the Western Cape, 2019)This thesis deals with the analysis and robust simulation of mathematical models describing Zika virus disease. Some background information about the occurrences of this disease and most recent literature indicating some ... -
Design, implementation and evaluation of a model for Service-learning in Pharmacy (SLIP) at a tertiary hospital
(University of the Western Cape, 2009)In recent years the focus of pharmacy practice has changed from being primarily 'drug-centred to' one which is 'patient-centred' (El-Awady et al., 2006, p. l ). Developments in pharmacy curricula worldwide are reflecting ... -
Design, implementation and evaluation of a model for service-learning in pharmacy (slip) at a Tertiary hospital
(2009)Background In recent years the focus of pharmacy practice has changed from being primarily ‘drugcentred to’ one which is ‘patient-centred’ (El-Awady et al., 2006, p.1). Developments in pharmacy curricula worldwide are ... -
The design, preparation and evaluation of Artemisia Afra and placebos in tea bag dosage form suitable for use in clinical trials
(University of the Western Cape, 2006)Artemisia Afra, a popular South African traditional herbal medicine is commonly administered as a tea infusion of the leaves. However, clinical trials proving it safety and efficacy are lacking mainly due to the absence ... -
Design, Synthesis and Evaluation of Indole Derivatives as Multifunctional Agents against Alzheimer's disease.
(University of the Western Cape, 2017)Alzheimer's disease (AD) is an age related neurodegenerative disorder characterised by progressive memory loss and cognitive impairment. It is one of several neurodegenerative disorders occurring as a result of a process ... -
Designing next generation high energy density lithium-ion battery with manganese orthosilicate-capped alumina nanofilm
(University of the Western Cape, 2015)In the wide search for advanced materials for next generation lithium-ion batteries, lithium manganese orthosilicate, Li₂MnSiO₄ is increasingly gaining attention as a potential cathode material by virtue of its ability to ... -
Detecting Baryon Acoustic Oscillations with HI Intensity Mapping using MeerKAT
(University of the Western Cape, 2019)Future radio surveys as the Square Kilometer Array (SKA) and its precursor, the "Meer" Karoo Array Telescope (MeerKAT), will map the Neutral Hydrogen (HI) in large areas of the sky using the intensity mapping (IM). HI ... -
Detecting Galaxies in the Epoch of Reionization
(University of the Western Cape, 2017)The aim of this project was to develop a technique that allows us to measure the redshift of radio galaxies in the Epoch of Reionization. We achieved this by constructing a parameterization of the 21-cm absorption feature ... -
Detecting patterns of upwelling variability in Eastern Boundary Upwelling Systems with special emphasis on the Benguela region
(University of Western Cape, 2020)Coastal upwelling is one of the most important oceanographic processes relating to ecosystem function at local and global spatial scales. To better understand how changes in upwelling trends may occur in the face of ongoing ... -
Detecting patterns of upwelling variability in Eastern Boundary Upwelling Systems with special emphasis on the Benguela region
(University of the Western Cape, 2020)Coastal upwelling is one of the most important oceanographic processes relating to ecosystem function at local and global spatial scales. To better understand how changes in upwelling trends may occur in the face of ongoing ... -
The detection of meningococcal disease through identification of antimicrobial peptides using an in silico model creation
(University of the Western Cape, 2019)Neisseria meningitidis (the meningococcus), the causative agent of meningococcal disease (MD) was identified in 1887 and despite effective antibiotics and partially effective vaccines, Neisseria meningitidis (N. meningitidis) ... -
Detection of phycotoxins along the South African coast: a comparison of three different biological assay systems and instrumental analysis by high performance liquid chromatography
(University of the Western Cape, 1998)In recent years, harmful algal blooms have been of growing concern in many parts of the world. These blooms often result in deterioration in water quality, large-scale mortalities in marine life, and shellfish poisonings ... -
Detection of positive selection resulting from Nevirapine treatment in longitudinal HIV-1 reverse transcriptase sequences
(University of the Western Cape, 2006)Nevirapine (NVP) is a cheap anti-retroviral drug used in poor countries worldwide, administered to pregnant women at the onset of labour to inhibit HIV enzyme reverse transcriptase. Viruses which may get transmitted to ... -
Detection of selective tyrosinase inhibitors from some South African plant extracts of lamiaceae family
(University of the Western Cape, 2016)Various dermatological disorders, such as formation of black pigmented patches on the surface of the skin arise from the over-activity of tyrosinase enzyme's degenerative action. This enzyme is further implicated in the ... -
Detection of selective Tyrosinase inhibitors from some South African plant extracts of Lamiaceae family
(University of the Western Cape, 2016)Various dermatological disorders, such as formation of black pigmented patches on the surface of the skin arise from the over-activity of tyrosinase enzyme's degenerative action. This enzyme is further implicated in the ... -
Determinants of access and utilization of health care facilities among women in South Africa: The case of the Eastern Cape province
(University of the Western Cape, 2022)Access to healthcare is a requirement for human well-being. However, women who seek medical care when needed are still confronted with significant access barriers. This study aimed to identify the factors influencing the ... -
Determinants of contraceptive use among currently married women in Amhara and Oromiya Regions of Ethiopia
(University of the Western Cape, 2009)The purpose of this research is to study the effect of different demographic and socio economic factors on the contraceptive use among currently married women of age 15-49 in the two regions of Ethiopia, Amhara (17,214,056) ... -
Determinants of female labour force participation in South Africa in 2008
(2009)South Africa’s female labour supply increased substantially over almost the past two decades. Female labour force participation is an imperative indication of the extent to which females participate in the economic activities ...