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Phytochemical and biological studies of Helichrysum cymosum
(University of the Western Cape, 2020)
Diabetes mellitus (DM) is well known as a group of systemic metabolic disorders with a considerable mortality rate around the world. Hyperglycemia is the main consequence of DM, which results from the shortage in insulin ...
Signalling molecule “calcium” improves germination and growth of Sorghum bicolor seedlings under salt stress
(University of the Western Cape, 2021)
Abiotic stress, mainly in the form of extreme temperatures, drought and salinity has caused major crop losses worldwide, putting a severe strain on agriculture. Salinity severely limits plant growth and productivity and ...
Novel norbornane derivatives as potential neuroprotective agents
(University of Western Cape, 2020)
Neurodegenerative disorders are characterised by progressive loss of the brain’s physiological
functions as a result of gradual degeneration of neurons in the central nervous system. Even
though they are classified as ...
The impact of different storage temperatures and storage period on the antioxidant activity of pomegranate
(University of Western Cape, 2021)
Fruit storage at cold temperatures is normally used to delay decay while maintaining the fruit’s quality. However, storage at low temperatures for a prolonged period causes some important metabolic functions within the ...
The effects of silver nanoparticles on the expression of protein biomarkers of cell stress, apoptosis and inflammation by the human liver cancer cell line, HepG2
(University of Western Cape, 2021)
Nanoscience is the study of phenomena and objects at the nanoscale (around 1-100 nm), socalled
nanomaterials. These nanomaterials exhibit novel properties that are often very
different to those of the bulk materials used ...
Differential toxicity of two murine endothelial cells to ROS duress: Understanding oxidative stress-induced blood-brain barrier dysfunction
(University of the Western Cape, 2020)
The blood-brain barrier (BBB) is a critical interface between the blood circulation and brain tissue which performs critical selection of circulating molecules that gain access to the brain tissue. Its unique ability to ...
The role of p-coumaric acid on physiological and biochemical response of chia seedling under salt stress
(University of the Western Cape, 2020)
The role of phenolic acids in mitigating salt stress tolerance have been well documented. However, there are contradicting reports on the effect of exogenously applied phenolic acids on the growth and development of various ...
Chalcone and curcumin hybrids of indole propargylamines as multifunctional neuroprotective agents
(University of the Western Cape, 2020)
Neurodegenerative disorders (NDs) are a range of chronic brain disorders that includes
amongst others motor function loss. Parkinson’s disease (PD) is one of the common NDs that
has an insidious onset and diagnosed when ...
Chemical isolation and electro-chemical characterization of antidiabetic compounds from selected South African lamiaceae plant species
(University of the Western Cape, 2020)
Diabetes mellitus (DM), being one of the most common metabolic disorders with an elevated morbidity and mortality rate around the world. It is characterised by deficiency in insulin secretion or degradation of secreted ...