Faculty of Natural Science: Recent submissions
Now showing items 101-120 of 2593
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Design of a thermoresponsive hydrogel for enhanced intratumoral permeation of a chemotherapeutic agent in oral squamous cell carcinoma
(University of the Western Cape, 2023)Introduction: Oral squamous cell carcinoma is the most common and aggressive cancer occurring in the oral cavity. Intravenous chemotherapy remains a pivotal part of treatment for the disease; however, these drugs cause ... -
Biosurfactant screening through metagenomic and culture-based approaches
(University of the Western Cape, 2022)The biosurfactant market is still predominantly represented by the three main products: surfactin, sophorolipids, and rhamnolipids, mainly as a result of the high cost and low yield associated with biosurfactant production. ... -
Spatial and temporal dynamics of flows and pools along non-perennial rivers in arid and semi-arid areas, South Africa
(University of the Western Cape, 2023)This study aimed to assess the use of multi-source remotely sensed data for monitoring the spatial distribution and dynamics of pools in two distinct sites (Touws and Molototsi) in South Africa. Various water extraction ... -
Machine learning approaches to study star formation and black hole accretion in the Meerkat/MIGHTEE survey
(University of the Western Cape, 2023)Galaxy formation and evolution are driven by two main physical processes: star formation and black hole accretion. Both processes can be traced via the synchrotron emission at radio wavelengths. However, a reliable ... -
Use of remotely sensed data and spatial modelling techniques to assess impacts of different land management practices on surface water quality
(University of the Western Cape, 2023)The study uses remote sensing and statistical techniques in assessing land use land cover impacts on surface water quality in the Heuningnes Catchment, Cape Agulhas, South Africa. Firstly, a review of the advancements made ... -
Green synthesis of silver nanoparticles using honey from the meliponinae stingless bee species and antibacterial studies.
(University of the Western Cape, 2023)Green synthesis of silver nanoparticles (AgNPs) is an environmentally friendly approach for preparing nanoparticles using biological sources as the reducing agent. Apart from using plant extracts, honey, that is used in ... -
Assessing the surface water - groundwater interaction and its influence on the water quality from headwaters to lowlands
(University of the Western Cape, 2023)The connections between surface water and groundwater systems remain poorly understood in many catchments throughout the world and yet they are fundamental in effectively managing water resources. Managing water resources ... -
Quantum dots for multiplexed biological imaging
(University of the Western Cape, 2023)Over the past two decades, indium phosphide (InP) colloidal quantum dots (QDs) have attracted substantial interest as a possibly less hazardous alternative to cadmium-based QDs. The improvements in their colloidal synthesis ... -
The presence and concentration of antiretroviral drugs in different water bodies around the Western Cape
(University of the Western Cape, 2023)Concerns regarding the prevalence of chemicals from medicines and personal care goods, such as cosmetics, in streams and rivers have grown in recent years. Water quality experts and environmentalists are becoming increasingly ... -
Exploring low-cost solution for 3D crime scene data gathering with immersive technology
(University of the Western Cape, 2023)3D crime scene data gathering is critical for law enforcement and investigators during crime scene investigations. Crime scene investigations have seen the effective usage of Light Detection and Ranging (LiDAR) scanners ... -
Geochemical and petrographic evidence for the vredefort proximal impact ejecta in the Northern Cape, South Africa
(University of the Western Cape, 2022)The advancement of the understanding of hypervelocity impacts lies in discovering impact structures and both proximal and distal impact ejecta. This study uses petrographic and geochemical techniques to investigate the ... -
Organometallic improvement of some tuberculosis drugs
(University of the Western Cape, 2023)Metal-based drugs are preferred motifs that serve as major pharmacophores in bioactive compounds for a variety of diseases, including as tuberculosis (TB). Heterocyclic, Schiff bases, aliphatic amines and other ligands ... -
Constraining the stratigraphy and paleotectonic development of the Cango Caves and Kansa Groups (Western Cape, South Africa) using detrital zircon and whole-rock geochemistry
(University of the Western Cape, 2022)The Saldania Belt is a Neoproterozoic to early Paleozoic low-grade orogenic belt that borders the southern and southwestern margins of the Kalahari Carton. It forms part of the Neoproterozoic Pan-African and Brasiliano ... -
An electrophysiological exploration into the Sertoli cell, utilizing plant extracts with a view to contraception
(University of the western cape, 2003)Certa in medicinal plant extracts have been shown to have a contraceptive effect on male rats (Rajasekaran et al. , 1988) and mice (Kong et al., 1986). A possible site for the mechanism of action has been identified as the ... -
Effect of inhaled cationic poly-peptides on respiratory mechanics in the isolated perfused rat lung
(University of the Western Cape, 1998)The inhalation route is increasingly being considered as a viable option to deliver protein drugs into the body, but there has been few studies dealing with the safety of this strategy. The results of in vitro studies have ... -
The antimicrobial screening of four South African asteraceae species and the preliminary structural investigation of an antipseudomonal compound from Arctotts auriculata
(University of the Western Cape, 1998)Infectious diseases represent one of the main causes of morbidity and mortality in developing countries, like South Africa. The indiscriminate use of antibiotics has also resulted in the emergence of a number of resistant ... -
Inclusive (p, α) and (p,³He) cross sections induced by 100 MeV protons on ⁴⁰Ca
(University of the Western Cape, 2006)Alpha clusteri ng in nuclei is studied with quasi - free knockout reactions. A beam of 100 MeV polarized protons was used in the quasi-free knockout reaction 40 ~a( p,p' a)36 Arat iThemba LABS. While the scattered protons ... -
The molecular characterization of trichoplusia ni single nucleocapsid nucleopolyhedrovirus: a study on early regulatory features
(University of the Western Cape, 2003)With the development of biological insecticides, many research efforts have been made in baculoviruses to investigate fundamental molecular aspects of these viruses, such as the function and regulation of genes, genome ... -
The antimicrobial screening of four South African Asteraceae species and the preliminary structural investigation of an antipseudomonal compound from Arctotis auriculata
(University of the Western Cape, 1998)Infectious diseases represent one of the main causes of morbidity and mortality in developing countries, like South Africa. The indiscriminate use of antibiotics has also resulted in the emergence of a number of resistant ... -
Regulatory attributes of the carotenoid biosynthetic pathway in Arabidopsis Thaliana under abiotic stress
(University of the Western Cape, 2012)Carotenoids are tetraprenoid (C40) molecules synthesized in plants, fungi, bacteria and algae, via the carotenoid biosynthetic pathway (CBP). Some carotenoids are readily converted to vitamin A (VA) in humans, e.g. ...