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The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
(University of the Western Cape, 2014)
The aim of the study was to detect the prevalence of AV and its associated bacteria with preterm delivery in the Western Cape, South Africa. Furthermore, it sought particularly to examine and investigate the predictive ...
The effects of nanomaterials, in the presence and absence of serum proteins, on testicular cell metabolic processes and steroidogenesis
(University of the Western Cape, 2014)
The aim of this study is to be the first to ascertain the effects of silver nanoparticles on testosterone production. The Ag NPs used for this study have the following characteristics; purity ≥ 99.5%; 66.7 % of particles ...
The effect of cissampelos capensis extract on prostate cancer, sertoli and leydig cell function
(University of the Western Cape, 2014)
This study investigated the effect of the C. capensis extract (0.001, 0.01, 0.1, 1, 10, 100 1000 μg/ml) on LNCaP prostate cancer, TM3 Leydig and TM4 Sertoli cells for 24 and 96 hours. The following parameters were investigated: ...
The effect of maternal oral health on pregnancy outcomes
(University of the Western Cape, 2014)
Adverse pregnancy outcomes such as preterm birth and low birth weight are major causes of maternal and neonatal morbidity and mortality. Increasing evidence points to an association between periodontal disease and adverse ...
Holarrhena floribunda leaves as a potential source of bioactive anticancer compounds
(University of the Western Cape, 2014)
Cancer is one of the leading causes of morbidity and mortality in developed and developing nations. It is estimated that 86% of new cases and 64% of death due to cancer are from Africa and 13.1 million deaths are estimated ...
In vitro modulatory effects of fermented rooibos extract (Aspalathus linearis) against ethanol-induced effects on the mouse blood-brain barrier
(University of the Western Cape, 2014)
Alcohol abuse is a growing crisis within South Africa, with severe health and socio-economic implications. Alcohol compromises the function of the blood-brain barrier (BBB), and thus its ability to regulate the homeostatic ...
The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro
(University of the Western Cape, 2014)
Conjugated linoleic acids (CLA) are geometrical and positional isomers of n-6 octadecadenoic acid (linoleic acid, LA, 18:2n-6), which form part of a family of essential polyunsaturated fatty acids (PUFA). There are 28 ...
Assessment of raw and treated sewage using in vitro assays
(University of the Western Cape, 2014)
Water scarcity is becoming an increasingly relevant problem for urban centres, especially in Southern Africa. However, water availability is not the only concern for consumers, because water quality is just as relevant. ...
Hyperactivation in human semen and sperm subpopulations by selected calcium modulators
(University of the Western Cape, 2014)
A functional sperm is critical for successful fertilization in order to deliver an intact genome to the site of fertilization. It is often characterized by high motility and normal morphology. Moreover, sperm hyperactivated ...
In vitro effects of rooibos herbal tea (Aspalathus linearis) against methamphetamine on the mouse blood brain barrier
(University of the Western Cape, 2014)
Methamphetamine (MA), also known as ‘Tik’, has detrimental short- and long-term psychological and morphological effects on the central nervous system (CNS). The lipophilic nature of MA allows it to cross the blood-brain ...