Browsing Magister Scientiae - MSc (Medical BioSciences) by Title
Now showing items 49-68 of 160
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The effect of Nicotine exposure on aspects of liver Carbohydrate metabolism
(University of the Western Cape, 1989)The liver plays an important role in maintaining the blood glucose concentration. In this respect glycogenolysis and gluconeogenesis play an important role. Interference with these pathways may therefore have an effect on ... -
The effect of nigella sativa oil on male reproductive function in male Wistar rats exposed to an obesogenic diet
(University of Western Cape, 2020)Obesity is a growing public health concern globally, particularly in developed countries such as the United States (US). More than 30% of Americans are considered obese. In the past 20 years in America, incidence of ... -
The effect of rooibos and green tea flavnoids on the physiology of TM3 Leydig cells
(University of the Western Cape, 2018)Camellia sinensis (C.sinesis) and Aspalathus linearis (A.linearis) are popular beverages consumed in many countries. Consumption of these plants may protect against cardiovascular disease, neurodegenerative disease, various ... -
The effect of sunitinib on neuroblastoma and glioblastoma cell growth
(University of the Western Cape, 2020)Cancer is a global health catastrophe, with neuroblastoma, the most common solid childhood tumor, and glioblastoma, a deadly brain tumor, being aggressive and unresponsive to current treatment modalities. These tumors are ... -
The effects of carbon-based nanoparticle surface functionalization on immune responses
(University of the Western Cape, 2022)Nano-based technologies are highly desired for the unique properties achieved through size restrictions. Nanoparticles (NPs) achieve a higher surface-to-volume ratio during synthesis. As a result there is a greater rate ... -
The effects of doxorubicin loaded chitosan-alginate nanoparticles on SK-N-BE(2) neuroblastoma cells
(University of the Western Cape, 2022)Cancer is a life-threatening disease and one of the leading causes of death globally. Cancer was thought to be associated with developed countries only but it is increasingly becoming a major health challenge in developing ... -
The effects of Elytropappus rhinocerotis Cass and Pelargonium triste (L.) L'Hèrit on animal health and metabolism
(University of the Western Cape, 2003)Many South Africans use cultural traditions and practices in the management of their health. Elytropappus rhinocerotis is an important medicinal plant, which is widely distributed in regions of South Africa. The objective ... -
The effects of Ethanol and Aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)The blood brain barrier (BBB) is a signaling interface between the blood and the central nervous system (CNS), which prohibits the entry of harmful blood-borne substances into the brain micro-environment, thus maintaining ... -
The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)The blood brain barrier (BBB) is a signaling interface between the blood and the central nervous system (CNS), which prohibits the entry of harmful blood-borne substances into the brain micro-environment, thus maintaining ... -
The effects of Exomis micriphylla and Atriplex lindleyi on metabolism and health
(University of the Western Cape, 2002)For many decades people have used plants for healing various ailments. Plant products have been used in herbal remedies especially for their anti-infective properties. The following study was undertaken to assess the ... -
Effects of graphene oxide nanoparticles on the immune system biomarkers produced by RAW 264.7
(University of the Western Cape, 2019)Graphene oxide (GO) is a single carbon layer, oxygen bearing graphene derivative, containing hydroxyl and carboxyl groups. Graphene oxide nanoparticles (GONPs) are promising nanomaterials for a variety of applications such ... -
Effects of green, black and rooibos tea, coffee and buchu on testosterone production by mouse testicular cultures
(University of the Western Cape, 2013)Modulation of the male reproductive system occurs as a result of exposure to endocrine disrupting compounds (EDCs) in different life stages. The effects of EDCs on the male reproductive system include infertility, decreased ... -
The effects of hypoxis hemerocallidea on blood glucose levels in rats with Type 2 diabetes
(University of the Western Cape, 2015)About 180 million people have been estimated to suffer from type 2 diabetes (T2DM) in 2006 and the annual death rate due to this disease was 3 million by that time. More than 400 medicinal plants used for the treatment ... -
The effects of maternal nicotine exposure during pregnancy or lactation on hypertension of the offspring
(University of the Western Cape, 2016)Blood pressure and heart rate is known to increase during smoking. These effects are specifically associated with nicotine while the other components of tobacco smoke seem to be of minor importance. It is becoming increasingly ... -
The effects of nanomaterials, in the presence and absence of serum proteins, on testicular cell metabolic processes and steroidogenesis
(University of the Western Cape, 2014)The aim of this study is to be the first to ascertain the effects of silver nanoparticles on testosterone production. The Ag NPs used for this study have the following characteristics; purity ≥ 99.5%; 66.7 % of particles ... -
The effects of PGA2 on cell cycle progression in oesophageal carcinoma cells
(University of the Western Cape, 2003)The molecular mechanisms causing anti-mitotic and cytotoxic effects of prostaglandin .A2 [PGA2 (CzoHroOa)] treatment of human oesophageal carcinoma (WHCO3) cells were investigated. WHCO3 cells, incubated with cytotoxic ... -
The effects of silver nanoparticles on the expression of protein biomarkers of cell stress, apoptosis and inflammation by the human liver cancer cell line, HepG2
(University of Western Cape, 2021)Nanoscience is the study of phenomena and objects at the nanoscale (around 1-100 nm), socalled nanomaterials. These nanomaterials exhibit novel properties that are often very different to those of the bulk materials used ... -
The effects of titanium oxide nanoparticles on cultured cells and the immune system
(University of Western Cape, 2021)Engineered nanomaterials derived from various bulk materials are being developed in ever larger quantities and with very diverse chemical compositions. The physical and chemical properties of the smaller nanoparticles are ... -
The effects of various combinations of different classes of anticancer drugs and tyrosine kinase inhibitors on the human MCF-7 breast carcinoma cell line
(University of the Western Cape, 2014)This study investigated the effects of TKIs on the growth and proliferation of MCF-7 breast carcinoma cells in culture. MCF-7 cells were exposed to different concentrations of TKIs alone and in combination with each other. ... -
The efficiency of drinking water treatment plants in removing immunotoxins
(University of the Western Cape, 2010)The aim of this study was to evaluate the effectiveness of water treatment processes of two drinking water plants to remove immunotoxins and steroid hormones. Raw and treated drinking water was screened for effects on ...