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Comparison between chemical and tissue culture methods to monitor environmental estrogens
(University of the Western Cape, 2012)
Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ...
The in vitro effects of pure and street methamphetamine on the proliferation and cell cycle of mouse brain endothelial (bend5) cells
(2012)
The blood-brain barrier (BBB) is an interface between the brain parenchyma and the circulating system. This barrier plays a vital role in protecting the CNS by restricting free paracellular diffusion of molecules from the ...
The in vitro effects of nicotine and selected antibiotics, tunicamycin and thapsigargin on human Breast carcinoma (mcf-7) cells.
(University of the Western Cape, 2012)
Cancer is defined as the abnormal growth of genetically mutated or perturbant cells. Nicotine is a known cancer promoter and an apoptotic suppressor. This alkaloid acts on the nicotinic acetylcholine receptors which affects ...
Immunohistochemical analysis of a panel of human and murine markers on xenografted human vaginal mucosa: a comparative study
(University of the Western Cape, 2012)
Athymic nude mouse models have been extensively used to study biological behaviour of normal and diseased human tissues. In such models, immune-deficient mice act as hosts for cysts constructed from human material. A unique ...
The effect of flavonoids on the in vitro activity of antibiotics against Staphylococcus aureus
(University of the Western Cape, 2012)
Staphylococcus aureus is a Gram-positive coccus belonging to the Stapylococcaeae family. S. aureus causes a wide range of infections that range from skin infections to lifethreatening infections such as pneumonia and ...
The effect of maternal nicotine exposure on cellular senescence in the lungs of the offspring
(University of the Western Cape, 2012)
Several studies conducted in laboratories at the University of the Western Cape has demonstrated an interference with the parenchymal lung tissue of the offspring when exposed to nicotine (smoking cigarettes and/or Nicotine ...
Production of cytokines in human whole blood after incubation with the nucleocapsid protein of the NL63 Coronavirus
(University of the Western Cape, 2012-11)
The Coronaviridae family consists of RNA viruses within the order Nidovirales. The family is
classified into two genera, namely the corona- and toroviruses. Coronaviruses are enveloped,
single stranded, positive sense ...
Expression of human coronavirus NL63 and SARS-CoV nucleocapsid proteins for antibody production
(University of the Western Cape, 2012)
Human Coronaviruses (HCoVs) are found within the family Coronaviridae (genus, Coronavirus) and are enveloped, single-stranded, positive-sense RNA viruses. Infections of humans by coronaviruses are not normally associated ...
Prevalence and characterization of Gardnerella vaginalis in pregnant mothers with a history of preterm delivery
(University of the Western Cape, 2012)
Risk factors such as intrauterine and vaginal infection put pregnant women at risk for delivering preterm. Bacterial vaginosis (BV) is a polymicrobial clinical syndrome commonly diagnosed in women of reproductive age, with ...
Investigations on the in vitro effects of aqueous Eurycoma longifolia Jack extract on male reproductive functions
(University of Western Cape, 2012)
Introduction:
Eurycoma longifolia (Tongkat Ali; TA) is a Malaysian shrub used to treat various
illnesses including male infertility. Considering that TA is also used to improve
male fertility and no report regarding ...