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Now showing items 81-90 of 93
Red palm oil as a therapeutic agent in triple-negative breast cancer patients
(University of the Western Cape, 2020)
Purpose: Breast cancer is one of the most frequent and fatal diseases women all around the globe are challenged with today. In women, breast cancer has the highest mortality rate of all cancers and the incidence rate is ...
The effect of sunitinib on neuroblastoma and glioblastoma cell growth
(University of the Western Cape, 2020)
Cancer is a global health catastrophe, with neuroblastoma, the most common solid childhood tumor, and glioblastoma, a deadly brain tumor, being aggressive and unresponsive to current treatment modalities. These tumors are ...
Paediatric non-alcoholic fatty pancreas disease and aortic intimal medial thickness: A study identifying potential fatty infiltration of the pancreas and its association with aortic IMT in children exposed to teratogens during pregnancy
(University of the Western Cape, 2020)
The incidence of non-communicable diseases is increasing worldwide, with South Africa being no exception. Non-communicable diseases are classified as non-infectious and are often referred to as lifestyle diseases as they ...
Mercury leaching from dental amalgam fillings and its association with urinary zinc
(University of the Western Cape, 2019)
Mercury (Hg) is an example of a toxic metal that is not essential for nutrition. It exists in organic and inorganic forms in seafood and vapour from dental amalgam fillings respectively. Elemental mercury (Hg0) from dental ...
The role of arylamine N-acetyltransferase 1 (NAT1) in the clinical therapy of tuberculosis
(University of the Western Cape, 2017)
Despite attempts to develop new drugs to reduce the worldwide mortality rate attributable to
tuberculosis (TB), the illness remains a threat. Isoniazid (INH) has been used as a frontline
drug for decades. However, several ...
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
(University of the Western Cape, 2018)
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
Over the years, microorganisms have become resistant to commonly used antimicrobial agents leading to multidrug resistance. ...
The effects of selective inhibitors of N-Glycosylation and Endoplasmic Reticulum stress inducers on Neuroblastoma cell proliferation and Apoptosis
(University of the Western Cape, 2017)
Among all childhood cancers diagnosed, neuroblastoma (NB) is the most prevalent during
infancy. In patients younger than 15 years, it accounts for more than 7% of malignancies and
about 15% of all paediatric mortalities. ...
The potential neuroprotective effects of two South African plant extracts in hydrogen peroxide-induced neuronal toxicity
(University of the Western Cape, 2018)
Background: Oxidative stress induced by reactive oxygen species has been strongly associated with many neurodegenerative diseases (NDDs) and many medicinal plant-derived products have been reported to exert potent antioxidant ...
The potential therapeutic role of palm oil on prostate cancer
(University of the Western Cape, 2020)
Prostate cancer is one of the heterogeneous groups of neoplastic diseases originating from the reproductive system of the male naming, the prostate gland. In the west, prostate cancer is the most common cancer affecting ...
Radioprotective effects of rooibos herbal tea on the developing central nervous system of wistar rats
(University of the Western Cape, 2018)
Background: Early postnatal radiation exposure from environmental, diagnostic or therapeutic
sources is potentially deleterious to the developing nervous system resulting in oxidative stress,
structural damage, altered ...