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Purification and characterisation of plasmodium falciparum Hypoxanthine phosphoribosyltransferase
(University of the Western Cape, 2007)
Malaria remains the most important parasitic disease worldwide. It is estimated that over 500 million infections and more that 2.7 million deaths arising from malaria occur each year. Most (90%) of the infections occur in ...
Transcriptional regulatory networks in the mouse hippocampus
(University of the Western Cape, 2007)
Neurological diseases are socially disabling and often mortal. To efficiently combat these diseases, a deep understanding of involved cellular processes, gene functions and anatomy is required. However, differential ...
Functional analysis of the mouse RBBP6 gene using Interference RNA
(University of the Western Cape, 2007)
The aim of this thesis was to investigate the cellular role of the mouse RBBP6 gene using the interference RNA (RNAi) gene targeting technology and also to understand the relevance of two promoters for the RBBP6 gene.
Differentials and disparities in the costs of major hospital procedures in South Africa: A structural analysis from the perspective of the supply side
(University of the Western Cape, 2007)
The aim of this study was to examine the extent to which providers' practices affect the cost of hospital procedures incurred by patients. The spsecific objective was to explore the magnitude of variations and statistically ...
Three-dimensional structure of a type III glutamine synthetase by single particle reconstruction
(University of the Western Cape, 2007)
This study represents the first structural investigation of any type III glutamine synthetase (GS). The GS, GlnA, from the medically important opportunistic human pathogen Bacteroides fragilis was studied with a view to ...