Browsing Department of Biochemistry by Author "Hide, Winston"
Now showing items 1-3 of 3
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The development and application of informatics-based systems for the analysis of the human transcriptome
Kelso, Janet (University of the Western Cape, 2003)Despite the fact that the sequence of the human genome is now complete it has become clear that the elucidation of the transcriptome is more complicated than previously expected. There is mounting evidence for unexpected ... -
Low detection of exon skipping in mouse genes orthologous to human genes on chromosome 22
Chern, Tzu-Ming (University of the Western Cape, 2002)Alternative RNA splicing is one of the leading mechanisms contributing towards transcript and protein diversity. Several alternative splicing surveys have confirmed the frequent occurrence of exon skipping in human genes. ... -
Novel genomic approaches for the identification of virulence genes and drug targets in pathogenic bacteria
Gamieldien, Junaid (University of the Western Cape, 2001)While the many completely sequenced genomes of bacterial pathogens contain all the determinants of the host-pathogen interaction, and also every possible drug target and recombinant vaccine candidate, computational tools ...