Browsing School of Pharmacy by Subject "Chloroquine resistance"
Now showing items 1-3 of 3
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Evaluation of antihistamines for in vitro antimalarial activity against Plasmodium falciparum
(2010)The declining efficacy of antimalarial drugs against resistant Plasmodium falciparum strains in several endemic regions has amplified the world’s burden of neglected diseases. This has highlighted the need for alternate ... -
Novel aminoquinoline-polycyclic hybrid molecules as potential antimalarial agents
(University of the Western Cape, 2014)Plasmodium falciparum malaria continues to be a worldwide health problem, especially in developing countries in Africa and is responsible for over a million fatalities per annum. Chloroquine (CQ) is low-cost, safe and was ... -
Selection, synthesis and evaluation of novel drug-like compounds from a library of virtual compounds designed from natural products with antiplasmodial activities
(University of the Western Cape, 2020)Malaria is an infectious disease which continues to kill more than one million people every year and the African continent accounts for most of the malaria death worldwide. New classes of medicine to combat malaria are ...