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Selection, synthesis and evaluation of novel drug-like compounds from a library of virtual compounds designed from natural products with antiplasmodial activities
(University of the Western Cape, 2020)
Malaria is an infectious disease which continues to kill more than one million people every year and the African continent accounts for most of the malaria death worldwide. New classes of medicine to combat malaria are ...
An investigation into combined amorphous form of sufadoxine, pyrimethamine and azithromycin
(University of Western Cape, 2021)
Malaria remains one of the top mortality causes in the sub-Saharan African region, especially
among pregnant women and infants. Despite several measures being implemented within the
affected areas such as the use of ...
Structure-Based Virtual Screening of Selected Malaria Box Compounds Against a Multi-Staged Protein (Falstatin) in Plasmodium falciparum
(University of the Western Cape, 2021)
Malaria disease poses substantial health risks to many nations, especially in Africa, where it primarily affects pregnant women, children, and immunocompromised patients. However, current antimalarial drugs have limitations ...