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Now showing items 11-20 of 109
Cardiovascular effects, molecular docking and chemo informatics analysis of compounds isolated from leonotis leonurus
(University of the Western Cape, 2015)
Leonotis leonurus (L. Leonurus) has relatively abundant diterpenes and has been used as a traditional herbal medicine for treating several ailments including influenza, muscular cramps, skin related diseases, menstrual, ...
Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability
(University of the Western Cape, 2016)
Background: Zidovudine (AZT) is a very useful drug for the management of Human
Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. ...
A qualitative evaluation on the appropriateness of the current regulatory guidelines, on the manufacture of medicines within the radiopharmaceutical industry
(University of the Western cape, 2016)
The purpose of this research thesis, is to evaluate the appropriateness of the current regulatory guidelines on the manufacture of medicinal products within the radiopharmaceutical industry. The manufacture of radiopharmaceuticals ...
Stability of freeze-dried aqueous and other modified extracts of Leonotis leonurus
(University of the Western Cape, 2017)
Leonotis leonurus, a South African indigenous medicinal plant, is frequently used in the form of a tea. However, this dosage form has many disadvantages. Consequently three L. leonurus solid extract preparations were ...
Investigation of the antidiabetic activity of Cnicusbenedictus L. in rats
(University of the Western Cape, 2016)
Diabetes Mellitus, one of the major diseases affecting human population all over the
world has caused significant morbidity and mortality. The management of this
condition has raised the demand of safe and cost effective ...
Electronic nicotine delivery systems : approach to regulation in South Africa
(University of the Western Cape, 2015)
Background: The explosion in the popularity and use of e- cigarettes over the last decade has raised concerns and incited intense discussions over their safety, efficacy and potential public health impact. Globally there ...
Paving a way to effectively regulate African traditional medicines in South Africa
(University of the Western Cape, 2017)
BACKGROUND:
Following the historical suppression of traditional medicines in South Africa, the
government published their National Health Plan in 1994 which made provision for
traditional healing as an integral and ...
Traditional, complementary and alternative medicine in Botswana: patients’ attitudes, knowledge and use
(University of the Western Cape, 2017)
BACKGROUND:
The purpose of this study was to determine use, knowledge and attitudes towards
traditional, complementary and alternative medicine (TCAM) in Botswana among people
who visit public health facilities.
PRIMARY ...
Challenges facing researchers conducting clinical trials in HIV prevention in South Africa: a focus on adherence
(University of the Western Cape, 2014)
In clinical trials, adherence of the participants to the dosing instructions is a major challenge. Many researchers have identified medication adherence as a topic to further explore in order to obtain good, usable and ...
A literature review on pharmacovigilance systems in off-label use of medicines
(University of the Western Cape, 2015)
Problem and significance: Off-label use of medicines is not illegal; however, it can be risky and harmful, or beneficial and innovative. The main problem of this practice is the lack of systems for monitoring adverse drug ...