School of Pharmacy: Recent submissions
Now showing items 81-100 of 225
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Disposal of unused medicines from households in Cape Town
(University of Western Cape, 2019)Evidence indicates that most South African households do not dispose of unused medicines in the manner prescribed by the medicine’s regulatory authority. This trend is not unique to South Africa, but several developing ... -
The formulation and characterisation of corticosteroid loaded Ethosomes for topical delivery
(University of the Western Cape, 2020)Background/Introduction: Atopic dermatitis (AD) is one of the most prevalent diseases worldwide. It is a rapidly growing field of study with several research avenues to explore its pathophysiology and to find innovative ... -
Transparency in medicines registration decision making: A closer look at National Medicines Regulatory Authorities (NMRAs) within the Southern African Development Community (SADC) region.
(University of the Western Cape, 2020)Medicines registration decision-making and regulatory best practice involve transparent and consistent rule making and processes with publicly available published assessment decisions and reports (Kaine, 2020). Publication ... -
Adverse Foetal Outcomes in Gestational Diabetes: A Systematic Review and Meta-analysis
(University of the Western Cape, 2020)Gestational diabetes mellitus (GDM) is a condition that affects pregnant women and is one of the most common complications related to pregnancy. According to the World health organisation (WHO), the usual window for ... -
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ... -
The impact of universal health coverage and national health expenditure on the main health determinants on central America countries and the Caribbean
(University of Western Cape, 2020)Health is considered as a sensitive marker of the sustainable development of a population. In Central America and Caribbean (CAC) region, the majority of countries are considered middle-income economies with significant ... -
Synthesis and evaluation of fluorescently linked polycyclic cage derivatives for application in neurodegenerative disorders
(University of the Western Cape, 2020)Neurodegenerative diseases (ND) are chronic and progressive in nature, and characterized by the gradual loss of neurons in various regions of the central nervous system (CNS). ND include Alzheimer's disease (AD), Parkinson's ... -
Evaluation of rational use of medicines in public healthcare facilities
(University of the Western Cape, 2020)Access to quality healthcare in South Africa is known to be unequal, with those who can afford it, receiving the best quality healthcare services in the private sector, and those who cannot afford it, having to receive ... -
Additional regulatory review pathways can facilitate faster dossier approvals in South Africa
(University of the Western Cape, 2019)The objective of the study was to perform a comparative review of pathways, timelines and improvements of countries with markets that the South African Health Products Authority (SAHPRA) benchmark themselves against. ... -
The effect of dossier farming on medicine registration in South Africa.
(University of the Western Cape, 2020)In this study, the researcher wanted to determine the effect of dossier farming in medicine registration in South Africa by comparing the number of generic registrations of products tendered for the government for the ... -
Mobile phone applications targeted towards medicine adherence in Africa: A systematic review
(University of Western Cape, 2020)According to the WHO (2017), non-communicable diseases (NCDs) which include stroke, cancer, heart disease, chronic respiratory disease and diabetes is the leading cause of death and is responsible for seventy one percent ... -
Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
(University of Western Cape, 2020)Natural products have been an important source of drugs and novel lead compounds in drug discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise to medicinally relevant agents. ... -
Medicine therapy management for diabetic club Patients at a primary health care clinic: exploring a Potential role for pharmacists
(University of the Western Cape, 2019)Diabetes mellitus is a complex chronic condition and has become a major public health concern worldwide. Many diabetic patients are accessing primary health care (PHC) clinics for diabetes care. Diabetic patients who are ... -
Synthesis and evaluation of 7-substituted 3-propargylamine coumarin derivatives as multifunctional monoamine oxidase and cholinesterase inhibitors for Alzheimer’s Disease treatme
(University of Western Cape, 2020)Alzheimer’s Disease (AD) is a neurodegenerative disease which results from the irreversible loss of neurons in the brain. The disease is characterized by progressive cognitive impairment with recurrent short-term memory ... -
Employee Perceptions of Corporate Social Responsibility within the Pharmaceutical Industry
(UWC, 2020)The role corporate social responsibility (CSR) plays amongst employees is underrated within the pharmaceutical industry, which focuses predominantly on external stakeholders and financial gain. The impact of CSR on these ... -
The effectiveness of using pictograms and text on medication labels at primary healthcare facilities in Cape Town
(University of the Western Cape, 2020)Medication labels are often the only information available to patients after obtaining medication 3 from the pharmacy or other healthcare practitioners. Inappropriately designed medicine labelling 4 contributes to poor ... -
Novel norbornane derivatives as potential neuroprotective agents
(University of Western Cape, 2020)Neurodegenerative disorders are characterised by progressive loss of the brain’s physiological functions as a result of gradual degeneration of neurons in the central nervous system. Even though they are classified as ... -
Isolation and Bioassay evaluation of Angiotensin Converting Enzyme inhibitory compounds of Centella asiatica
(University of the Western Cape, 2019)Hypertension is by far the most common risk factor for cardiovascular disease (CVD), which has been identified as the leading cause of death worldwide and a major economic burden in developing countries. Over the years, ... -
Moving towards social accountability in pharmacy education: Exploring service-learning outcomes and opportunities with Cape Town community health forum representatives
(University of the Western Cape, 2020)The University of the Western Cape (UWC), School of Pharmacy has embedded service-learning in the undergraduate curriculum in an attempt to align activities with the social accountability values. Third-year pharmacy students ... -
Moving towards social accountability in pharmacy education: what is the role of the practising pharmacist?
(University of the Western Cape, 2020)The World Health Organisation (WHO) has stated that “there is no health without a workforce” (Campbell et al., 2013). The health workforce is essential for every health care system. The availability, accessibility and ...