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Now showing items 61-70 of 121
Investigating the functional interaction of transcription regulator card of mycobacterium tuberculosis with ribonucleic acid polymerase
(2013)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ...
Actinobacterial and archaeal diversity in lake Magadi, Kenya
(University of the Western Cape, 2013)
Microorganisms of the class Actinobacteria and domain Archaea are interesting from a
biotechnological perspective owing to their metabolic attributes as producers of
secondary metabolites and resilience under harsh ...
Targeted delivery of embelin to cancer cells
(University of the Western Cape, 2013)
Apoptosis or programmed cell death is vital to the development of organisms as they
maintain the balance between cell death and cell growth. Failure to activate apoptosis has
been implicated in carcinogenesis and often ...
Evaluating the specancer cell targeting peptides for applications in cancer diagnostics
(University of the Western Cape, 2013)
Cancer is a disease most often associated with poor prognosis. During the development of the
disease, cells acquire genetic mutations which result in changes in bio-molecules (DNA and
protein), thus altering normal ...
Impact of vanadium stress on physiological and biochemical characteristics in heavy metal susceptible and tolerant Brassicaceae
(University of the Western Cape, 2013)
There is an influx in heavy metals into soils and ground water due to activities
such as increased mineral mining, improper watering and the use of heavy metal
contaminated fertilizers. These heavy metals are able to ...
Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
(2013)
The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ...
Functional characterisation of a thermophilic cellulase from a Malawian metagenomic library
(2013)
Biofuels are currently recognised as the most viable source of energy to replace
depleting fossil fuel reserves, with bioethanol the most popular alternative alcohol fuel.
Producing bioethanol from agricultural waste ...
Identification of endophytic bacterial communities associated with South African crops: sorghum bicolor (L. Moench), pennisetum glaucum and arachis villosulicarpa
(University of the Western Cape, 2014)
In this study, the diversity of endophytic bacteria associated with food crops, sorghum (Sorghum bicolor L. Moench), pearl millet (Pennisetum glaucum L.) and groundnut (Arachis villosulicarpa) is investigated using ...
Genetic diversity of the Organic Cation Transporter 1 gene within the Cape Coloured Population
(University of the Western Cape, 2012)
The aim of this study was to investigate the genetic diversity of the SLC22A1 gene and to deduce its possible pharmacogenetic implications within the Cape Coloured population of South Africa; a uniquely admixed population ...
Phytochemical and antimicrobial studies on Rhus natalensis
(2011)
Extracts from the root bark, stem bark, and leaves of R. natalensis were screened for antibacterial activity against standard bacterial strains; Staphylococcus aureas, Escherichia coli and Pseudomonas aureginosa, and fungi; ...