Magister Scientiae - MSc (Biotechnology)
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Recent Submissions
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De novo assembly of the rooibos genome
(University of Western Cape, 2020)Rooibos (Aspalathus linearis) is endemic to the Cederberg region of South Africa, and one of the few indigenous medicinal plants commercially cultivated in the country. International interest in rooibos is growing, and ... -
Nanoformulation of Artemisia afra and its potential biomedical applications in type 2 diabetes
(University of Western Cape, 2019)Current research classifies Type 2 diabetes as most prevalent non-communicable diseases in South Africa. Approximately 285 million people are affected globally with an expected increase to 595 million by the year 2035. ... -
Physiological and molecular characterization of wheat cultivars to Fusarium oxysporum infection
(University of the Western Cape, 2019)Biotic stress is one of the main causes for agricultural loss of economically important cereal crops. The increasing prevalence of biotic stress inflicted by fungal species such as Fusarium has significantly reduced yields ... -
Silica Coated Core-Shell Quantum Dot-based Electro-Immunosensor for Interferon Gamma TB Disease Biomarker
(University of the Western Cape, 2020)Tuberculosis (TB) is a disease that results from infection by Mycobacterium tuberculosis, which is regarded the most common infecting organism. TB has killed countless numbers of people particularly in underdeveloped ... -
Physio-biochemical characterization of two wheat cultivars to Fusarium proliferatum infection
(University of the Western Cape, 2019)Wheat is a key global commodity in terms of acreage and tradeable value and as a staple in household diets. Many factors including biotic stress conditions have detrimental effects on global wheat production and yield. ... -
Evaluation of agronomic and drought response traits in two cultivars of soybean for cultivation in the Transkei region of the Eastern Cape
(University of Western Cape, 2020)Drought is a major stress that affects the productivity of plants across the globe. The consequences of drought are posed to continue reducing agricultural productivity as world climate changes. This makes it imperative ... -
Genetic analysis of mitochondrial DNA within Southern African populations.
(UWC, 2020)As human beings we are curious about our origin and ancestry. A curiosity has led to an investigation of human evolution and expansion across the world by means of population genetics and phylo-genetics by evaluating a ... -
Methylgyoxal signalling in Phaseolus vulgaris under phosphate deficiency
(UWC, 2020)In this study, we observed that phosphate (P) deficiency stunted plant growth and produced plants with poor morphological characteristics (yellow and small leaves). Furthermore, we treated plants with 0.8 mM (control) and ... -
Characterization of ATP-binding cassette drug transporters and their role in breast cancer treatment using in silico approach
(University of the Western Cape, 2019)Breast cancer is the most common cancer in women worldwide, and is the second most common cancer in the world, responsible for more than 500 000 deaths annually. Estimates are that 1 in 8 women will develop breast cancer ... -
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects
(University of the Western Cape, 2020)Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ... -
Development and validation of a pharmacogenomics profiling panel suitable for personalizing Metformin therapy
(University of the Western Cape, 2019)The burden of non-communicable diseases (NCDs) in South Africa is predicted to increase substantially in the next decades if the necessary preventative measures are not taken. The two most common NCDs associated with rapid ... -
Isolation and characterization of stem endophytic bacteria from weed plants for enhancing Vanadium tolerance in Brassica napus
(University of the Western Cape, 2019)Bacterial endophytes are able to improve the growth of their hosts through a number of different mechanisms such as nutrient uptake regulation, plant hormone production and regulation, siderophore production and phosphate ... -
Identification and characterisation of sorghum bicolor heme oxygenase-1 (sbho1) gene and its role in conferring biotic and abiotic stress tolerance to plants
(University of the Western Cape, 2019)Biotic and abiotic stresses such as herbivore attack, pathogen infection, salinity, drought, cold, heat and UV radiation, are unfavourable conditions that affect plant growth and productivity globally (Fedoroff et al., ... -
The geographical analysis of the mitochondrial DNA control region found in southern African population's by using a bioinformatics approach
(University of the Western Cape, 2020)South Africa’s demographic complexity has been historically shaped by interethnic admixture between the native KhoiSan inhabitants and the Bantu expansion that started 3000 - 5000 YBP and reached South Africa about 1000 ... -
Responses of maize antioxidant enzymes to drought stress
(University of the Western Cape, 2019)Maize (Zea mays L) was subjected to drought stress for 28 days. The effects of the drought stress on growth, H2O2 content and lipid peroxidation were investigated and the activities of antioxidant enzymes [superoxide ... -
Development and validation of a pharmacogenomics profiling panel suitable for personalizing metformin therapy
(University of the Western Cape, 2019)The burden of non-communicable diseases (NCDs) in South Africa is predicted to increase substantially in the next decades if the necessary preventative measures are not taken. The two most common NCDs associated with ... -
Responses of maize Antioxidant Enzymes to drought stress
(University of the Western Cape, 2019)Maize (Zea mays L) was subjected to drought stress for 28 days. The effects of the drought stress on growth, H2O2 content and lipid peroxidation were investigated and the activities of antioxidant enzymes [superoxide ... -
Biogenic synthesis of gold nanoparticles using red and green pear fruit extracts
(University of the Western Cape, 2019)There has been a growing interest in the design of biocompatible and environmentally affable nanoparticles (NPs) among scientists to develop novel and safe biomaterials for use in various biomedical applications. This can ... -
Development of an aptamer based lateral flow test strip for a diabetes biomarker
(University of the Western Cape, 2019)Diabetes mellitus is one of the major chronic diseases that poses a significant risk to human health globally. Current diagnostics for diabetes are based on blood glucose measurements, which can go unnoticed for years. ... -
The antimicrobial activity of zinc oxide nanoparticles synthesized with plant extracts against Staphylococcus aureus
(University of the Western Cape, 2019)Nanoparticles using a green synthesis production method is of increasing interest for biomedical applications. Zinc oxide is currently used in medicinal and cosmetic formulations, and zinc oxide nanoparticles have potential ...
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