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Now showing items 101-110 of 169
The effect of blocking selected endocytic mechanisms on heterologous protein secretion in the yeast saccharomyces cerevisiae
(University of the Western Cape, 2018)
The yeast Saccharomyces cerevisiae is considered a good host used for heterologous protein production due to the organism’s microbial safety, rapid growth and eukaryotic post- translational processing. As a fermentative ...
Nanoformulation of Artemisia afra and its potential biomedical applications in type 2 diabetes
(University of Western Cape, 2019)
Current research classifies Type 2 diabetes as most prevalent non-communicable diseases in South
Africa. Approximately 285 million people are affected globally with an expected increase to 595
million by the year 2035. ...
Identification of novel miRNAs as diagnostic and prognostic biomarkers for prostate cancer using an in silico approach
(University of the Western Cape, 2017)
Cancer is known as uncontrollable cell growth which results in the formation of
tumours in the areas that are affected by the cancer. There are two types of tumours:
benign and malignant. This study focus is on prostate ...
Polyethylene glycol (PEG) induced water stress alters the physiological and molecular responses of chia plants
(The University of the Western Cape, 2017)
Water deficit is known to be one of the most detrimental environmental factors
to affect crop production and growth in South Africa. This factor has become
more apparent with increasing cases of drought in the country.
Developing a quantum dot nanotracker for endophytic bacteria translocation in plants
(University of the Western Cape, 2017)
Endophytes are bacteria that have been shown in previous studies to promote plant growth
without eliciting any sign of infection or plant disease, as well as promote bio-fortification
and has thus gained much attention ...
The identification of aptamers against serum biomarkers of human tuberculosis
(University of the Western Cape, 2018)
Tuberculosis (TB) is a global health problem and rated as the second leading cause of death after HIV/AIDS. Transmission of TB from one person to the next is very rapid in crowded communities. Therefore, it is crucial to ...
Evaluation of cytotoxic activity of gold nanoparticles naturally synthesised from South African indigenous medicinal plant extracts
(University of the Western Cape, 2018)
Nanotechnology has emerged as a promising field in the quest to address health conditions. Green nanotechnology is a fairly new branch of nanotechnology, which aims to produce and utilize nanomaterials in a way that is ...
Involvement of abscisic acid and H2O2 in antioxidant enzyme activities mediated by nitric oxide synthase-like activity in maize
(University of the Western Cape, 2018)
In recent years, nitric oxide (NO) has emerged as an important endogenous plant
signalling molecule that mediates many developmental and physiological
processes. NO regulates the activity of antioxidant enzymes in response ...
Exploring anti-tyrosinase bioactive compounds from the Cape flora
(University of the Western Cape, 2018)
Tyrosinase is an enzyme widely distributed in the biosphere and is found in many species of
bacteria, fungi, animals, and plants; it is associated with melanin production. Even though it
possesses many beneficial properties ...
Comparative analysis of 3, 3'- diindolylmethane and indole-3-carbinol respective treatments in Brassica napus L.
(University of the Western Cape, 2017)
Lately, there has been serious contamination of soils and ground water caused by mineral
mining and environmental pollution leading to heavy metal accumulation within soils and over
time rendering the soil infertile. The ...