Magister Scientiae - MSc (Biotechnology): Recent submissions
Now showing items 121-140 of 264
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Investigating the effect of particle size on the antibacterial activity of gold nanoparticles
(University of the Western Cape, 2017)The increase of antibiotic- and/or multidrug-resistant bacteria has become a major global challenge. Killing of antibiotic-resistant bacteria requires a high dose of multiple, expensive drugs, which possess unfavourable ... -
Investigation of the Stress-Induced Nuclear Localisation of Retinoblastoma Binding Protein 6 (Rbbp6) and its Role in Ubiquitination Of Y-Box Binding Protein-1 (Yb-1)
(University of the Western Cape, 2017)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa RING finger-containing human protein known to serve as an E3 ubiquitin ligase, and to play a role in ubiquitination and suppression of the tumour suppressor p53. It ... -
Investigating the effect of particle size on the antibacterial activity of gold nanoparticles
(University of the Western Cape, 2017)The increase of antibiotic- and/or multidrug-resistant bacteria has become a major global challenge. Killing of antibiotic-resistant bacteria requires a high dose of multiple, expensive drugs, which possess unfavourable ... -
Expression of stress-tolerance related genes in Saccharomyces cerevisiae producing heterologous cellobiohydrolase.
(University of the Western Cape, 2017)Cellulose is the most abundant naturally occurring renewable biopolymer on earth and a major structural component in plant cell walls, making it an ideal source of renewable energy. Consolidated bioprocessing (CBP) is a ... -
Exogenous caffeic acid alters molecular responses in Salvia hispanica L.
(University of the Western Cape, 2016)Salt stress is one of the most important abiotic stresses, resulting in the accumulation of ROS, which amount to great agricultural losses by influencing plant yield and in turn threaten sustainable agriculture and food ... -
Effects of exogenous myristic acid on growth and germination of Brassica napus L. under zirconium toxicity
(University of the Western Cape, 2016)Lipids when exogenously applied are known to cause various changes in ROS levels produced within plants. They can either be beneficial to the plant when not stimulating the overproduction of ROS thus resulting in improved ... -
The inhibition of nitric oxide biosynthesis alters anti-oxidant capacity in soybean
(University of the Western Cape, 2016)Nitric oxide is a signalling gaseous molecule endogenously synthesized from various enzymatic and non-enzymatic sources in plants. It is known to play a crucial role in the regulation of plant physiological processes ... -
Effect of Fusarium oxysporum on the physiological and molecular responses of cowpea plants
(The University of the Western Cape, 2017)Cowpea is a tropical, drought-tolerant legume crop that is indigenous to Africa. The crop is of nutritional importance to both animals and humans as part of their diet. Stress to crop plants is defined as any factor that ... -
Polyethylene glycol (PEG) induced water stress alters the physiological and molecular responses of chia plants
(The University of the Western Cape, 2017)Water deficit is known to be one of the most detrimental environmental factors to affect crop production and growth in South Africa. This factor has become more apparent with increasing cases of drought in the country. -
Developing a quantum dot nanotracker for endophytic bacteria translocation in plants
(University of the Western Cape, 2017)Endophytes are bacteria that have been shown in previous studies to promote plant growth without eliciting any sign of infection or plant disease, as well as promote bio-fortification and has thus gained much attention ... -
Comparative analysis of 3, 3'- diindolylmethane and indole-3-carbinol respective treatments in Brassica napus L.
(University of the Western Cape, 2017)Lately, there has been serious contamination of soils and ground water caused by mineral mining and environmental pollution leading to heavy metal accumulation within soils and over time rendering the soil infertile. The ... -
Structural Analysis of Induced Mutagenesis Protein B from Mycobacterium tuberculosis Jeremy
(University of the Western Cape, 2016)Knowing the three-dimensional structure of a protein may be useful in understanding its function. In this study, induced mutagenesis protein B (ImuB) from Mycobacterium tuberculosis was analyzed using molecular biology and ... -
Characterization of the role of a cycloartenol synthase gene (ZMCAS494) in Zea mays responses to drought stress
(University of the Western Cape, 2016)Plant Sterols are an important part of the membrane and their role is to control cell membrane fluidity and permeability. Several studies have indicated that plants that are mutant for genes that play a role in the sterol ... -
Identification of novel miRNAs as diagnostic molecules for detection of breast cancer using in silico approaches
(University of the Western cape, 2017)Breast cancer (BC) is the most common cancer in women worldwide, and is the second most common cancer in the world, responsible for more than 500 000 deaths annually. Estimates are that 1 in 8 women will develop BC in their ... -
A comparative proteomic analysis of two contrasting Salvia hispanica L. genotypes under salinity stress
(University of the Western cape, 2016)Salvia hispanica L. is an annual pseudocereal food crop, locally known as chia that has the ability to grow in water stress environments. The importance of chia dates back to the pre-columbian era where it was consumed as ... -
Functional analysis of miRNA regulated genes in prostate cancer as potential diagnostic molecules
(University of the Western Cape, 2016)Prostate Cancer is the leading cause of cancer-related death in males in the Western world. It is a common biological disease originating from the reproductive system of the male namely, the prostate gland, usually in older ... -
Development of genotyping systems for pharmacogenomics profiling
(University of the Western Cape, 2016)Genetic variability in genes encoding drug metabolizing enzymes, transporters and targets are known to be the main factors of inter-individual differences in therapeutic outcome. Genetic factors are estimated to be responsible ... -
The assessment of the bactericidal effect of green synthesized silver nanoparticles against a panel of infectious microorganisms
(University of the Western Cape, 2016)The emergence of multiple drug resistant microorganisms poses a major threat to human life. These microorganisms have made the currently used antibiotics ineffective and therefore continue to thrive. Therefore, there is a ... -
Screening bacterial symbionts of marine invertebrates for ribosomally synthesized natural products
(University of the Western Cape, 2016)Pharmaceutical research and development strategies rely on the constant discovery of novel natural products as potential drugs. Recent studies have shown that the microorganisms associated with sponges are the true producers ... -
Actinobacterial diversity of the Ethiopian Rift Valley lakes
(University of the Western Cape, 2011)The class Actinobacteria consists of a heterogeneous group of filamentous, Gram-positive bacteria that colonise most terrestrial and aquatic environments. The industrial and biotechnological importance of the secondary ...