Philosophiae Doctor - PhD (Medical BioScience): Recent submissions
Now showing items 41-60 of 71
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Effects of Libyan traditional plants on the reproductive system of male and female rats
(University of the Western Cape, 2015)In different parts of the world, medicinal plants have demonstrated a lot of health benefits to mankind and remains an important source for the discovery of new bio-active compounds. Libya is a typical example of a country ... -
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
(University of the Western Cape, 2017)Over the years, microorganisms have become resistant to commonly used antimicrobial agents leading to multidrug resistance. This is believed to occur even with new classes of therapeutic agents thus creating a challenge ... -
Semen characteristics of free-ranging African elephants (Loxodonta africana) and Southern white rhinoceros (Ceratotherium simum simum) using Computer-aided sperm analysis, Electron microscopy and Genomics as diagnostic tools
(University of the Western Cape, 2016)The survival of free-ranging (in situ) African elephant and Southern white rhinoceros populations are currently being challenged on a daily basis in Africa. Reproductive health is considered a vital component of species ... -
Effects of Libyan traditional plants on the reproductive system of male and female rats
(University of the Western cape, 2015)In different parts of the world, medicinal plants have demonstrated a lot of health benefits to mankind and remains an important source for the discovery of new bio-active compounds. Libya is a typical example of a country ... -
Bionomics of vector-borne diseases in sites adjacent to lakes Victoria and Baringo in Kenya
(University of the Western Cape, 2016)Bionomics of vector-borne pathogens (VBPs) is a complex phenomenon that involves understanding the ecology of arthropod borne pathogens and vertebrate hosts potentially involved in their transmission cycles. Investigations ... -
Investigations on the effects of Typha capensis on male reproductive functions
(University of the Western Cape, 2016)Introduction: Typha capensis, commonly referred to as bulrush also called "love reed'' growing in Southern Africa's wetlands, is one of South Africa indigenous medicinal plants that are traditionally used to treat male ... -
Modulation of colon carcinogenesis by dietary ω-6/ω-3 fatty acid ratios : a chemopreventive strategy?
(University of the Western Cape, 2015)The aim of this study was to determine whether dietary fats constituting specific ω-6/ω-3 fatty acids (FA) ratio has chemopreventive modulating effects on the development of colon cancer. Western diets intake of saturated ... -
Structural and functional characterization of human DDX5 and its interaction with NS5B of hepatitis C virus
(University of the Western Cape, 2011)Hepatitis C was first recognized as a transfusion-associated liver disease not caused by hepatitis A or hepatitis B virus after serological tests were developed to screen for their presence in the blood. The infectious ... -
Ursolic acid and oleanolic acid as novel therapeutic agents in breast cancer
(University of the Western Cape, 2015)Breast cancer is one of the most common cancers among women in South Africa and the second leading cause of cancer death after lung cancer. According to the American Cancer Society 2015, women have a 12% chance of developing ... -
Potamanautes warreni biomarker assays to monitor silver nanomaterial contaminants in aquatic environments
(University of the Western Cape, 2016)There has been extensive growth in nanoscale technology in the last few decades to such a degree that nanomaterials (NMs) have become a constituent in a wide range of manufactured commercial and domestic products. This ... -
The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
(University of the Western Cape, 2014)The aim of the study was to detect the prevalence of AV and its associated bacteria with preterm delivery in the Western Cape, South Africa. Furthermore, it sought particularly to examine and investigate the predictive ... -
The effect of maternal oral health on pregnancy outcomes
(University of the Western Cape, 2014)Adverse pregnancy outcomes such as preterm birth and low birth weight are major causes of maternal and neonatal morbidity and mortality. Increasing evidence points to an association between periodontal disease and adverse ... -
Holarrhena floribunda leaves as a potential source of bioactive anticancer compounds
(University of the Western Cape, 2014)Cancer is one of the leading causes of morbidity and mortality in developed and developing nations. It is estimated that 86% of new cases and 64% of death due to cancer are from Africa and 13.1 million deaths are estimated ... -
Synergistic effects of mixtures of fungicides and medicinal plant extracts against Botrytis cinerea
(University of the Western Cape, 2008)We hypothesize that South African medicinal plants contain compounds that can act in synergism with synthetic antifungal compounds. Four fungicides - Sporekill™, Rovral™, Terminator™ and Teldor™ at doses 0.1, 0.2, 0.4 and ... -
Characterization of candida species isolated from the oral mucosa of HIV-positive African patients
(2013)One of the most common HIV-associated opportunistic infections is candidiasis, caused by Candida albicans or other Candida species. In immune suppressed subjects, this commensal organism can cause an increase in patient ... -
Phylogeography and speciation in the genus arthroleptella
(2009)Moss frogs are restricted to permanently moist terrestrial habitats in the south-western Cape Fold Mountains. There is a very close association between Arthroleptella distribution and Table Mountain Sandstone. Suitable ... -
The effect of nicotine and prostaglandin A2 on the lung cancer cell line NCI-H157
(2009)Lung cancer is the most common fatal cancer in terms of both incidence and mortality in the world. The most important cause of lung cancer is exposure to tobacco smoke through active or passive smoking. Nicotine which is ... -
Characterization of Candida species isolated from the oral mucosa of HIV-positive African patients
(UWC, 2013)One of the most common HIV-associated opportunistic infections is candidiasis, caused by Candida albicans or other Candida species. In immune suppressed subjects, this commensal organism can cause an increase in patient ... -
Sperm mitochondria: species specificity and relationships to sperm morphometric features and sperm function in selected mammalian species
(University of the Western Cape, 2011)Numerous studies on mammalian spermatozoa have reported large variations in the dimensions of the main sperm structural components, namely the head, midpiece and flagellum. These variations in sperm architecture are believed ... -
Effect of tea and herbal infusions on mammalian reproduction and fertility
(University of the Western Cape, 2013)Camellia sinensis (tea) and Aspalathus linearis (rooibos) may improve reproductive function owing to their antioxidant properties. To test this hypothesis, male and female rats were given 2% and 5% green tea (Gt), black ...