Philosophiae Doctor - PhD (Biochemistry)
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Recent Submissions
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Investigation of socio-demographic, clinical and genetic factors associated with blood pressure and glycaemic control among indigenous South African adult patients
(University of the Western Cape, 2021)Achieving blood pressure and glycaemic treatment targets remain a major public health challenge in individuals with hypertension and diabetes mellitus (DM). This research project was, therefore, designed to investigate the ... -
Investigation of the intra-cellular localisation of Retinoblastoma Binding Protein 6 using immunofluorescence microscopy
(University of the Western Cape, 2017)Human Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa protein that has been implicated in a number of crucial cellular processes. It forms part of the mRNA 3'-end processing complex in both humans and yeast, and it ... -
Metagenomic analysis and characterization of microbial diversity from hydrothermal samples of El Tatio geyser field, Chile
(University of the Western Cape, 2012)The El Tatio geyser field (ETGF) is the largest known geothermal field in Chile, forming part of a wide spectrum of extremophilic habitats in the country. The ETGF is NaCl rich, with high concentrations of toxic elements ... -
Novel genomic approaches for the identification of virulence genes and drug targets in pathogenic bacteria
(University of the Western Cape, 2001)While the many completely sequenced genomes of bacterial pathogens contain all the determinants of the host-pathogen interaction, and also every possible drug target and recombinant vaccine candidate, computational tools ... -
Physical and genetical investigation of the Xp11.3 region on the short arm of the human X-chromosome
(University of the Western Cape, 2004)The pattern of inactivation in the DXS8237E-UBE1-PCTK1 region is of particular interest, since the mechanisms of X chromosome inactivation and the escape from inactivation are, as yet, not fully understood. The inactivation ...
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