Browsing Faculty of Natural Science by Title
Now showing items 1642-1661 of 2560
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Molecular dynamic simulation studies of the South African HIV-1 Integrase subtype C protein to understand the structural impact of naturally occurring polymorphisms
(University of Western Cape, 2021)The viral Integrase (IN) protein is an essential enzyme of all known retroviruses, including HIV-1. It is responsible for the insertion of viral DNA into the human genome. It is known that HIV-1 is highly diverse with a ... -
The molecular evolution and epidemiology of Rubella virus
(University of the Western Cape, 2014)Despite widespread rubella virus (RV) vaccination programs, annually RV still causes severe congenital defects in an estimated 100,000 children globally. A concerted attempt to eradicate RV is currently underway and ... -
Molecular genetics: strategies to identify congenital cataract genes in captive-bred vervet monkeys
(University of the Western Cape, 2013)Molecular genetics: strategies to indentify congenital cataract genes in captive-bred Vervet monkeys Zandisiwe Emilia Magwebu MSc thesis, Department of Medical Biosciences, University of the Western Cape The present ... -
Molecular genetics: strategies to identify congenital cataract genes in captive-bred Vervet monkeys
(University of the Western Cape, 2012)The present study describes molecular aspects of inherited congenital cataract in captive-bred Vervet monkeys. Congenital cataracts are lens opacities that are present at birth or soon after birth and include hereditary ... -
A molecular investigation of the prevalence of suspected periodontopathogens and their association with preterm birth
(University of the Western Cape, 2010)More than 20 million infants in the world (15.5 % of all births) are born with low birth weight. Ninety-five % of them are in developing countries. Oral colonization of Gramnegative anaerobes has been implicated as a risk ... -
A molecular investigation of the prevalence of suspected periodontopathogens and their association with preterm birth
(University of the Western Cape, 2010)More than 20 million infants in the world (15.5 % of all births) are born with low birth weight. Ninety-five % of them are in developing countries. oral colonization of gram-negative anaerobes has been implicated as a risk ... -
''A molecular investigation of the prevalence of suspected periodontopathogens and their association with preterm birth.''
(University of the Western Cape, 2010)More than 20 million infants in the world (15.5 % of all births) are born with low birth weight. Ninety-five oZ of them are in developing countries. Oral colonization of Gramnegative anaerobes has been implicated as a risk ... -
Molecular modeling and simulation studies to prioritize sequence variants identified by whole-exome sequencing in a South African family with Parkinson's disease
(University of Western Cape, 2021)Parkinson’s disease (PD) is a neurodegenerative disorder that occurs due to a loss of dopaminergic neurons in the substantia nigra. It is one of the most common neurodegenerative disorders, ranking second only to Alzheimer’s ... -
Molecular, functional and biological characterization of a single enveloped nucleopolyhedrovirus infecting the crop pest Helicoverpa armigera
(University of the Western Cape, 2002)My study involves a detailed molecular and cellular characterisation of a South African isolate of a nucleopolyhedrovints (I.IPV) isolated from the Lepidopteran insect Helicoverpa armigera (HaSNPV-SA). Chapter two entails ... -
Molecularly imprinted polymer sensor systems for environmental estrogenic endocrine disrupting chemicals
(University of the Western Cape, 2018)There is growing concern on endocrine disrupting compounds (EDCs). The presence of drugs in water supplies was first realized in Germany in the early 1990s when environmental scientists discovered clofibric acid. Clofibric ... -
Molecularly imprinted polymers for detection of volatile organics associated with fuel combustion
(University of the Western Cape, 2018)Pollutants such as polycyclic aromatic hydrocarbons (PAHs) are known for their toxic effects which may lead to the cause of degenerative diseases in both humans and animals. PAHs are widespread in the environment, and may ... -
Monitoring and evaluation of medical products regulatory systems and harmonization in west Africa
(University of the Western Cape, 2023)The Food & Drug Authority (FDA) defined regulatory harmonization as a process where regulatory agencies align technical guidelines for marketing and the development of pharmaceutical products all over the world. Regulatory ... -
Monitoring lipid and haematological abnormalities in paediatric patients on antiretroviral therapy at a Community Health Centre in the Cape Metropole
(University of the Western Cape, 2014)South Africa faces a huge Human Immunodeficiency Virus (HIV) burden with more than 400,000 children currently on antiretroviral therapy (ART). Studies on lipid and haematological profile changes in paediatrics are of ... -
Monitoring of heavy metals in the Bottelary River using Typha capensis and Phragmites australis
(University of the Western Cape, 2005)The aim of this study was to use plants to determine the degree of heavy metal contamination in water and sediments in order to effectively monitor and provide possible recommendation to improve the water quality in the ... -
Monitoring of heavy metals in the bottelary river using typha capensis and phragmites australis
(2005)The aim of this study was to use plants to determine the degree of heavy metal contamination in water and sediments in order to effectively monitor and provide possible recommendation to improve the water quality in the ... -
Monitoring water quality with riparian trees along the Berg River, Western Cape
(University of the Western Cape, 2012)Heavy metals and nutrients have long been regarded as pollutants to freshwater ecosystems. These elements have a detrimental effect on plants, animals and the water quality of rivers in South Africa. The Berg River flows ... -
Mononuclear and multinuclear salicylaldimine metal complexes as catalysts precursors in the oxidation of phenol and cyclohexene
(2009)In this thesis typical homogeneous and dendritic immobilized catalysts derived from salicylaldimines were investigated as catalysts for the oxidation of hydrocarbons using hydrogen peroxide as oxidant under aerobic ... -
Monte carlo simulations of complex germanium escape suppression spectrometers with MCNPX a case study
(University of the Western Cape, 2009)Gamma ray spectroscopy has provided enormous amounts of information on the behaviour and structure of atomic nuclei [SHA88, BEA92, EBE08]. Most of the major discoveries in experimental nuclear physics over the last five ... -
The morphodynamic characteristics of erosional headcuts in Palmiet (Prionium serratum) wetlands
(University of the Western Cape, 2018)Gully erosion and headcut migration has been at the crux of wetland degradation in South Africa. The resulting erosion and draining effect has seen more than 50% of wetlands in the country degraded. This study investigated ... -
Moving towards social accountability in pharmacy education: Exploring service-learning outcomes and opportunities with Cape Town community health forum representatives
(University of the Western Cape, 2020)The University of the Western Cape (UWC), School of Pharmacy has embedded service-learning in the undergraduate curriculum in an attempt to align activities with the social accountability values. Third-year pharmacy students ...