Browsing Faculty of Natural Science by Author "Ferreira, Roux-Cil"
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Exploring the role of the “glycan-shield” of human immunodeficiency virus in susceptibility to, and escape from, broadly neutralising antibodies
Ferreira, Roux-Cil (University of the Western Cape, 2018)The HIV-1 envelope (Env) glycoprotein is the primary target of the humoral immune response and a critical vaccine candidate. However, Env is densely glycosylated and thereby substantially protected from neutralisation. ...