Browsing Faculty of Natural Science by Author "Onani, Martin"
Now showing items 1-14 of 14
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Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
Swartz, Lauren Taryn (2013)The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ... -
The effects of capping agents on the synthesis of magnetic-luminescent Fe₃O₄ -InP/ZnSe nanocomposite material
Paulsen, Zuraan (University of the Western Cape, 2015)Magnetic luminescent nanoparticles of an iron oxide (Fe₃O₄) superparamagnetic core and an indium phosphide/zinc selenide (InP/ZnSe) quantum dot shell are reported. The magnetic nanoparticles (MNP’s) and quantum dots (QD’s) ... -
Fabrication of luminescent nanocomposites for diagnosis of breast cancer
Ayabei, Kiplagat (University of the Western Cape, 2016)In this study we were able to synthesize separately iron oxide magnetic nanoparticles, InP/ZnSe and CdTe/ZnS quantum dots. The iron oxide nanoparticles were coupled with InP/ZnSe QDs to form the luminescent magnetic ... -
Fabrication of type-I indium-based near-infrared emitting quantum dots for biological imaging applications
Mushonga, Paul (University of the Western Cape, 2013)Semiconductor nanocrystals or quantum dots (QDs) are fluorescent nanometer-sized particles which have physical dimensions that are smaller than the excitonic Bohr radius, large surface area-to-volume ratios, broad ... -
Metallodendrimers as catalysts for C-C coupling reactions
Mapolie, S. F. (2011)In this work, we describe the synthesis of ferrocenylimine and G1 dendrimeric N,N′ ligands, and their palladium(II) complexes. The ligands L1 – L4 were synthesized following Schiff base condensation reactions. The ... -
Organometallic improvement of some tuberculosis drugs
Cwasi, Phelisa (University of the Western Cape, 2023)Metal-based drugs are preferred motifs that serve as major pharmacophores in bioactive compounds for a variety of diseases, including as tuberculosis (TB). Heterocyclic, Schiff bases, aliphatic amines and other ligands ... -
Some new bimetallic nickel and palladium complexes for catalysis applications
Van Wyk, Shane Cedrick (University of the Western Cape, 2015)This thesis reports on the syntheses of new bimetallic iminopyridyl nickel(II) and palladium(II) complexes as catalyst precursors for ethylene ligomerization/polymerization. Tetrahydrophenyl-linked iminopyridyl ligands, ... -
Synthesis & characterization of yttria-stabilised zirconia (YSZ) hollow fibre support for Pd based membrane
Bridget, Tshamano Matamela (University of the Western Cape, 2013)Inorganic based membranes which have a symmetric/asymmetric structure have been produced using an immersion induced phase inversion and sintering method. An organic binder solution (dope) containing yttria-stabilised ... -
Synthesis and characterization of iron oxide nanoparticles embedded on various polymers
Magqazolo, Siphesihle (University of the Western Cape, 2018)During the course of this study iron oxide nanoparticles, which have been researched for drug-targeted delivery, were synthesised via the co-precipitation method and characterised using various methods. This study focused ... -
Synthesis and characterization of pyridyl/quinolyl imine ruthenium(II) and palladium (II) complexes in catalysis
Swartz, Leoni Destine (University of the Western Cape, 2015)We report the successful syntheses of a family of tetradentate N-donor pyridyl and quinolyl-imine ligands N1,N2-bis((pyridin-2-yl)methylene)ethane-1,2-diamine (L1), N1,N3- bis(pyridin-2-ylmethylene)propane-1,3-diamine (L2), ... -
Synthesis and characterization of rhenium (vii) and rhuthenium (ii) dendritic catalysts: oxidative cleavage and epoxidation of alkenes
Busa, Asanda V. (2012)Herein we report the successful synthesis of a class of stable and flexible Schiff-base chelators capable of coordinating both ruthenium (II) and rhenium (VII) and which would be catalytically active for oxo-transfer ... -
Synthesis and characterization of zinc-doped magnetic nanoparticles for diagnostic studies
Allard, Garvin Richard Johan (University of the Western Cape, 2015)In the present study we report the synthesis and characterization of iron oxide magnetic nanoparticles doped with zinc in an attempt to enhance the magnetic properties. The nanoparticles were prepared via the co-precipitation ... -
Synthesis of peptide-loaded chitosan nanoparticles for the treatment of sexually transmitted infections (STI’s)
Phathekile, Bonke (University of Western Cape, 2019)Peptides are among the main drugs which attract much attention because of their great potential in treating sexually transmitted diseases and other chronic diseases. There has been a major challenge of delivering these ... -
Synthesis, optical and morphological characterization of pbse quantum dots for diagnostic studies: a model study
Ouma, Linda Achiengꞌ (University of the Western Cape, 2013)In this study PbSe quantum dots (QDs) were successfully synthesized via the organometallic and aqueous routes. Optical characterization was carried out using photoluminescence (PL) spectroscopy, structural and morphological ...