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The characterisation of human coronavirus nl63 proteins
(University of Western Cape, 2021)
Human Coronavirus NL63 (HCoV-NL63) is one of seven coronaviruses (CoVs) that cause respiratory disease in the global population. The Membrane (M) and Nucleocapsid (N) proteins are part of the core CoV-structural proteins, ...
Bioactive actinobacteria associated with two South African medicinal plants, Aloe ferox and Sutherlandia frutescens
(University of Western Cape, 2021)
Actinobacteria, a Gram-positive phylum of bacteria found in both terrestrial and aquatic environments, are well-known producers of antibiotics and other bioactive compounds. The isolation of actinobacteria from unique ...
Molecular dynamic simulation studies of the South African HIV-1 Integrase subtype C protein to understand the structural impact of naturally occurring polymorphisms
(University of the Western Cape, 2021)
The viral Integrase (IN) protein is an essential enzyme of all known retroviruses, including HIV-1. It is responsible for the insertion of viral DNA into the human genome. It is known that HIV-1 is highly diverse with a ...
Hybrid lead halide perovskite thin films and solar cells by chemical vapour deposition
(University of the Western Cape, 2021)
The organic-inorganic hybrid perovskites such as methyl ammonium lead iodide (MAPbI3) or mixed halide MAPbI3-xClx (x is usually very small) have emerged as an interesting class of semiconductor materials for their application ...
The influence of clay diagenesis on the petrophysical properties of sandstone reservoirs in the Pletmos Basin Offshore South Africa
(University of Western Cape, 2020)
Pletmos Basin is a Mesozoic half graben located in the southern part of South Africa and has undergone numerous tectonic changes which involve alteration of structure and reworking of sediments. Clay diagenesis has become ...
Molecular dynamic simulation studies of the South African HIV-1 Integrase subtype C protein to understand the structural impact of naturally occurring polymorphisms
(University of Western Cape, 2021)
The viral Integrase (IN) protein is an essential enzyme of all known retroviruses, including HIV-1. It is responsible for the insertion of viral DNA into the human genome. It is known that HIV-1 is highly diverse with a ...
Awareness regarding non-steroidal anti-inflammatory drug-related side effects in Johannesburg, South Africa
(University of Western Cape, 2021)
Non-steroidal anti-inflammatory drugs (NSAIDs) are amongst the most commonly used medications globally, as they are highly effective and easily accessible. The NSAIDs are indicated for mild to moderate pain management. The ...
Investigating phytoplankton fluctuations and drum filter effectiveness on an abalone farm in Hermanus, South Africa.
(University of the Western Cape, 2021)
Aquaculture is a growing industry in South Africa, with the production of abalone, Haliotis midae, at
the forefront. The Western Cape Province hosts 12 of the 18 abalone farms in South Africa, with a
concentration of ...
Security related self-protected networks: Autonomous threat detection and response (ATDR)
(University of Western Cape, 2021)
Cybersecurity defense tools, techniques and methodologies are constantly faced with increasing
challenges including the evolution of highly intelligent and powerful new-generation threats. The
main challenges posed by ...
Investigation of socio-demographic, clinical and genetic factors associated with blood pressure and glycaemic control among indigenous South African adult patients
(University of the Western Cape, 2021)
Achieving blood pressure and glycaemic treatment targets remain a major public health challenge in individuals with hypertension and diabetes mellitus (DM). This research project was, therefore, designed to investigate the ...