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Now showing items 111-120 of 159
Establishing a framework for an African Genome Archive
(University of Western Cape, 2019)
The generation of biomedical research data on the African continent is growing, with numerous studies realizing the importance of African genetic diversity in discoveries of human origins and disease susceptibility. The ...
The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples
(University of the Western Cape, 2019)
Ichthyophonus hoferi is a highly pathogenic histozoic parasite that has low host specificity capable of producing mass mortalities of epizootic proportions in marine commercial fish populations. Currently in Southern Africa, ...
Isolation and characterization of plant growth promoting endophytic bacteria from Medicago lupulina for enhanced drought tolerance in Maize
(University of the Western Cape, 2019)
Maize is one of the major staple foods in many African nations however, this crop is sensitive to environmental stressors. Drought is a major environmental stressor affecting maize production. Due to global warming, drought ...
Protein expression and antifungal effect of fluconazole-resistant Candida species following effective in vitro treatment with K21, a novel antifungal agent
(University of Western Cape, 2019)
Background: Oropharyngeal candidiasis, caused by the fungus Candida, is the most common
opportunistic infection affecting the quality of life of immunocompromised patients. Fluconazole
is widely used as the first line ...
Investigation of the auto-ubiquitination and ubiquitination potentials of Retinoblastoma binding protein 6 and its binding to p53
(University of Western Cape, 2019)
Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa human protein known to play an
essential role in mRNA 3’-end processing, as well as functioning as an E3 ligase to catalyze
ubiquitination and suppression of p53 and ...
Investigation of protein-protein interactions involving retinoblastoma binding protein 6 using immunoprecipitation and nuclear magnetic resonance spectroscopy
(University of Western Cape, 2019)
Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been
shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with
tumour suppressor proteins such as ...
Disposal of unused medicines from households in Cape Town
(University of Western Cape, 2019)
Evidence indicates that most South African households do not dispose of unused medicines in the
manner prescribed by the medicine’s regulatory authority. This trend is not unique to South Africa,
but several developing ...
Protection of Karst spring in Shanxi Region,China: A case study from Jinci Spring Catchment.
(University of Western Cape, 2019)
Groundwater is an important of water resources and plays a significant role in the water supply in most parts of the world. It is also an important ecological environment factor, and its variations often affect natural ...
Development of an aptamer based lateral flow test strip for a diabetes biomarker
(University of the Western Cape, 2019)
Diabetes mellitus is one of the major chronic diseases that poses a significant risk to human
health globally. Current diagnostics for diabetes are based on blood glucose measurements,
which can go unnoticed for years. ...
The impact of using technology through cooperative learning on learners’ performance on grade 11 circle geometry
(University of the Western Cape, 2019-11)
Euclidean geometry was recently re-introduced as a compulsory topic in the Mathematics
Curriculum for learners in the Further Education and Training (FET) band in 2012. The
diagnostic analysis reports on the National ...