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Now showing items 101-110 of 141
Synthesis of bimetallic immiscible alloy nanoparticles through green and gamma radiolysis approaches for environmental remediation applications
(University of the Western Cape, 2022)
The synthesis of bimetallic immiscible alloy nanoparticles (NPs) using versatile routes, is a major concern since physio-chemical methods are not environmentally benign. Breaking down the immiscibility would generate NPs ...
Next generation sequencing approaches for novel gene discovery in South African Parkinson’s disease families
(University of the Western Cape, 2022)
In the last decade, next-generation sequencing (NGS) approaches have revolutionised
the study of human genomics, particularly aiding the understanding of genetic diseases. Parkinson’s
disease (PD) is a complex neurodegenerative ...
Development of an operon detection algorithm to analyze gene regulation in drug resistant Mycobacterium tuberculosis
(University of the Western Cape, 2022)
In prokaryotes, operon structures often form to allow microorganisms to respond rapidly and efficiently to changing environmental conditions. Operons are sets of neighbouring genes which are co-regulated and co-transcribed. ...
Using CRISPR/Cas9 to construct consolidated bioprocessing strains from natural isolates of Saccharomyces cerevisiae
(University of the Western Cape, 2022)
Saccharomyces cerevisiae has gained much attention as a host for cellulosic bioethanol production using consolidated bioprocessing (CBP) methodologies, due to its high ethanol producing titres, heterologous protein producing ...
Synthesis and evaluation of metformin derivatives for anti-diabetes
(University of the Western Cape, 2022)
Type 2 diabetes mellitus (T2DM) is a significant public health crisis and is placed amongst the top ten leading causes of death worldwide. Metformin is the first-line drug used to treat T2DM, which is mainly attributed to ...
Investigation of common deficiencies observed in scientific assessments and the implementation of a new robust review pathway, the risk-based assessment approach, by the South African Health Regulatory Authority, SAHPRA
(University of the Western Cape, 2022)
The main objective of this study is to improve patient access to medicines. The research is two-fold, the
first component promotes transparency between the South African Health Products Regulatory
Authority (SAHPRA), ...
Mitigation of salinity stress using exogenously applied molybdenum in sorghum bicolor
(University of the Western Cape, 2022)
The agricultural sector is the main producer of food throughout the world. However, the constant changes in environmental conditions, such as extreme weather, droughts, and salinity have impacted this sector negatively ...
Demographic and health impact of alcohol and tobacco in Cameroon and Albania
(University of the Western Cape, 2022)
The aim of this article is to illustrate a comparative analysis of the prevalence of alcohol and
tobacco use and its impact on demographic and health indicators in Cameroon and Albania.
Tobacco is the leading cause of ...
Effect of synthetic methods on the characteristics and performance of IrO2 catalysts
(University of the Western Cape, 2022)
For many years fossil fuel has been the primary source of energy worldwide though, the
environment is negatively affected because of the high carbon dioxide (CO2) emissions
associated with the use of fossil fuels. Hydrogen ...
Analysis and simulation of some ecological models describing weed-water hyacinth dynamics in Lake Tana, Ethiopia
(University of the Western Cape, 2022)
The water hyacinth plant is notorious for being the world’s worst aquatic weed. In
Ethiopia, it invades lake Tana which is the largest lake in Ethiopia. This is attracting
attention of many researchers including mathematical ...