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Modelling the growth of large-scale structure with interacting fluids
(University of the Western Cape, 2015)
Prevailing astronomical and astrophysical observations suggest that we live in a spatially flat cold dark matter (CDM) universe - currently going through a period of accelerated expansion possibly driven by “dark energy” ...
Transport and fate of chemical and microbial tracers at University of Western Cape (UWC) campus site, Cape Flats aquifer of South Africa
(University of the Western Cape, 2016)
Extreme weather events in combination with geographical changes in groundwater
utilization, groundwater availability, aquifer recharge, and ultimately changes in the quality of water resources, are expected in the future. ...
Laser drilling of metals and glass using zero-order bessel beams
(University of the Western Cape, 2013)
This dissertation consists of two main sections. The first section focuses on generating zero order Bessel beams using axicons. An axicon with an opening angle y = 5⁰ was illuminated with a Gaussian beam of width ω₀ = 1.67 ...
The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
(University of the Western Cape, 2014)
The aim of the study was to detect the prevalence of AV and its associated bacteria with preterm delivery in the Western Cape, South Africa. Furthermore, it sought particularly to examine and investigate the predictive ...
The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)
The blood brain barrier (BBB) is a signaling interface between the blood and the
central nervous system (CNS), which prohibits the entry of harmful blood-borne
substances into the brain micro-environment, thus maintaining ...
In silico and molecular validation of identified putative genes and functional analysis of a N K G2D ligand as a breast cancer biomarkers
(University of the Western Cape, 2015)
The current diagnostic, prognostic, predictive and therapeutic monitoring methods
used for breast cancer are limited. Thus, research into more specific, sensitive and
effective strategies is required. Breast cancer is ...
Matrix comparison of isolation conditions for secondary metabolite producing marine sponge associated bacteria
(University of the Western Cape, 2015)
The discovery of novel secondary metabolites has declined significantly in recent years whereas there is a rise in the number of multi-drug resistant pathogens and other types of diseases. The decline in natural product ...
Dissolution and antiviral activity of a novel nevirapine formulation
(University of the Western Cape, 2014)
The author’s objective was to follow the product life-cycle process of a novel antiretroviral, nevirapine formulation in South Africa, to generate and compile data to pursue market registration. Five supramolecular ...
Identification of microRNAs as a class of biomarkers for the early diagnosis of prostate cancer : an in silico and molecular approach
(University of the Western Cape, 2015)
Prostate cancer (PCa) is the second most common form of cancer in men around
the world. In many parts of Africa, data on prostate cancer is sparse. This is
attributed to poor access to testing and diagnostics. The ...
Some non-standard statistical dependence problems
(University of the Western Cape, 2016)
The major result of this thesis is the development of a framework for the application
of pair-mixtures of copulas to model asymmetric dependencies in bivariate data. The main motivation is the inadequacy of mixtures of ...