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The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ...
Identification and characterisation of potential virulence genes of Salmonella from rooibos tea
(University of the Western Cape, 2015)
The aim of this study was to investigate the presence of Salmonella in the tea processing environment, to identify and detect potential virulence genes isolated from Salmonella in the tea, and to determine the antibiotic ...
A dual analysis of the South African Griqua population using ancestry informative mitochondrial DNA and discriminatory short tandem repeats on the Y chromosome
(University of the Western Cape, 2015)
The primary objective of this Masters project was to investigate the maternal ancient substructure of the Griqua population in South Africa. Genetic ancestry was determined by investigating ancestry informative single ...
Determination of total organic carbon content using Passey’s ΔLogR method in coals of the Central Kalahari Karoo Basin, Botswana.
(University of the Western Cape, 2016)
The Kalahari Karoo Basin is one of several basins in southern Africa filled with Late Carboniferous to Jurassic sediments that are primary targets for Permian aged coal. In order to determine the Coalbed Methane (CBM) ...
Integrating regulatory and methylome data for the discovery of clear cell Renal Cell Carcinoma (ccRCC) variants
(University of the Western Cape, 2015)
Kidney cancers, of which clear cell renal cell carcinoma comprises an estimated 70%, have been placed amongst the top ten most common cancers in both males and females. With a mortality rate that exceeds 40%, kidney cancer ...
The use of chemostratigraphy and geochemical vectoring as an exploration tool for platinum group metals in the Platreef, Bushveld Igneous Complex, South Africa : a case study on the Tweefontein and Sandsloot farms
(University of the Western Cape, 2015)
The Platreef is known for its complexity and its heterogeneous lithologies, coupled with an unpredictable PGE and BMS mineralisation. The motivation behind this study was to aid mining geologists in targeting mineralisation ...
The effects of capping agents on the synthesis of magnetic-luminescent Fe₃O₄ -InP/ZnSe nanocomposite material
(University of the Western Cape, 2015)
Magnetic luminescent nanoparticles of an iron oxide (Fe₃O₄) superparamagnetic core and an indium phosphide/zinc selenide (InP/ZnSe) quantum dot shell are reported. The magnetic nanoparticles (MNP’s) and quantum dots (QD’s) ...
Modulation of brassica rapa L. antioxidant activities by exogenous methylglyoxal under zirconium stress
(University of the Western Cape, 2016)
With a decrease in water availability and arable land, and the ever-increasing reports of toxic chemical pollutants, it is crucial to elucidate plants’ mechanisms of adaptability to these abiotic stressors. South Africa ...
In vitro investigation of the ubiquitination and degradation of p53 by Murine Double Minute 2 (MDM2) and Retinoblastoma Binding Protein 6 (RBBP6)
(University of the Western Cape, 2015)
P53 is one of the most important tumour suppressor proteins in the body which protects the cell against the tumourigenic effects of DNA damage by initiating processes such as apoptosis, senescence and cell cycle arrest. ...
Durability studies of membrane electrode assemblies for high temperature polymer electrolyte membrane fuel cells
(University of the Western Cape, 2011)
Polymer electrolyte membrane fuel cells (PEMFCs) among other fuel cells are considered the best candidate for commercialization of portable and transportation applications because of their high energy conversion and low ...