Browsing Magister Scientiae - MSc (Medical BioSciences) by Title
Now showing items 14-33 of 160
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The association of mercury from dental amalgam with urinary selenium
(University of the Western Cape, 2017)Background: Dental amalgam has been the traditional material for filling cavities in teeth. Mercury (Hg) is a component of dental amalgam, from where it is continuously released and deposited in different tissues, mostly ... -
A baseline evaluation of the cytotoxicity of gold nanoparticles in different types of mammalian cells for future radiosensitization studies
(University of the Western Cape, 2020)Recently nanoparticles (NPs) have been introduced and used in combination with therapeutic approaches to develop nanotechnology-enabled medicine. These nanostructures allow for the exploitation of the physiochemical ... -
A baseline evaluation of the cytotoxicity of gold nanoparticles in different types of mammalian cells for future radiosensitization studies
(University of the Western Cape, 2020)Recently nanoparticles (NPs) have been introduced and used in combination with therapeutic approaches to develop nanotechnology-enabled medicine. These nanostructures allow for the exploitation of the physiochemical ... -
Brine shrimp lethality test and acetylcholine esterase inhibition studies on selected South African medicinal plants
(University of the Western Cape, 2012)Research into traditional medicines is often conducted in a multidisciplinary approach as motivated by a desire to understand them in as complete a manner as possible,realizing their chemistry, biology and pharmacology. ... -
CIMT and cardiovascular risk in five-year-old children in a low socioeconomic population exposed to alcohol and nicotine during pregnancy: a case-control study
(University of the Western Cape, 2020)Cardiovascular diseases (CVD) are among the top 10 causes of death in all ages in South Africa. The prevalence of maternal smoking and alcohol consumption during pregnancy is alarmingly high in South Africa. In utero ... -
Circadian activity rhythms and early gene expression in the suprachiasmatic nucleus of a diurnal rodent, Rhabdomys pumilio
(UWC, 2001)Although humans are diurnal in behavior, animal models used for the study of circadian rhythms are mainly restricted to nocturnal rodents. This study focused on circadian behavior and gene expression in a diurnal rodent ... -
Cloning and characterization of the human coronavirus NL63 nucleocapsid protein
(University of the Western Cape, 2011)The human coronavirus NL63 was discovered in 2004 by a team of researchers in Amsterdam. Since its discovery it has been shown to have worldwide spread and affects mainly children, aged 0-5 years old, the immunocompromised ... -
Cloning and expression of human cyclophilin A and its interaction with human coronavirus NL63 nucleocapsid protein
(University of the Western Cape, 2011)Coronaviridae family is composed of a number of ribonucleic acid (RNA)-containing viruses currently classified into two genera, the coronavirus and torovirus. The family is classified together with the Arteviridae in the ... -
Cloning and expression of the M-gene from the human coronavirus NL-63 in different expression systems
(University of the Western Cape, 2008)Respiratory tract infections are one of the leading causes of morbidity and mortality across the world. This is especially true for infants, young children, the elderly and the immunocompromised. The strain placed on ... -
Cloning of Human Coronavirus NL-63 ORF3, M and E genes for antibody production
(University of the Western Cape, 2010)Human Coronavirus NL-63 is a respiratory virus with a high incidence rate, causing mild respiratory infections in children under the age of 18. The outbreak of Sever Acute Respiratory Syndrome (SARS) in 2003 sparked increased ... -
Comparative in vitro study of the anti-cancer effect of apricot and peach kernel extracts on human colon cancer cells
(University of the Western Cape, 2015)Amygdalin, a controversial anti-cancer agent, is a cyanogenic glycoside plant compound found in apricot and peach kernels. Both amygdalin and its patented form, Laetrile®, have been promoted and sold as "vitamin B-17", ... -
Comparison between chemical and tissue culture methods to monitor environmental estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
Comparison between chemical and tissue culture methods to monitor environmental Estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
A comparison of some aspects of the masticatory apparatus of the cape mole-rat, Georychus capensis with that of the cape dune molerat, Bathyergus suillus
(2009)Some African mole-rats of the family Bathyergidea have dramatically different ecological niches which may cause selective anatomical adaptations. Bathyergus suillus lives in sandy soil and eats a wide range of food whereas ... -
The development of a sars-cov-2 pseudoparticle assay for the detection of neutralizing antibodies in sera from covid-19 patients
(University of the Western Cape, 2024)The COVID-19 pandemic has caused devastating effects on the global socio-economic landscape. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19, and infections have led to ... -
Dexamethasone's impact on LPS-induced inflammation of blood-brain barrier endothelial cells
(University of the Western Cape, 2023)The blood-brain barrier (BBB) serves as a protective and regulatory barrier between the blood and the brain. Microvascular endothelial cells provide homeostatic regulation of the central nervous system (CNS). BBB integrity ... -
The distribution of the desert rain frog (breviceps macrops) in South Africa
(2009)The Distribution of the Desert Rain Frog (Breviceps macrops) in South Africa Kirsty Jane Bell M.Sc. Thesis, Department of Biodiversity and Conservation Biology, University of the Western Cape. The desert rain frog (Breviceps ... -
Do physiotherapy students employ evidence-based practice in the management of musculoskeletal disorders and sports injuries
(2013)Background: Musculoskeletal disorders (MSD’s) and sports injuries are commonly sustained throughout the world daily. They are dominant in many countries, with considerable cost involvement and impact on quality of life. ... -
Does maternal nicotine exposure during gestation and lactation change the oxidant-antioxidant status of the lungs of the offsprings and is tomato juice protecting the lungs of the offsprings?
(University of the Western Cape, 2009)Nicotine exposure to the fetus through tobacco smoking or nicotine replacement therapy during the whole period of gestation and lactation causes diverse effects on fetal and neonatal lung development, integrity and maturation ... -
Does Olea africana protect the heart against ischemiareperfusion injury?
(2009)Cardiovascular disease is a major health problem and remains the number one cause of death worldwide. For centuries, medicinal plants have been used in different cultures as medicines for the treatment and control of various ...