Browsing Magister Scientiae - MSc (Medical BioSciences) by Title
Now showing items 38-57 of 160
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The effect of doxorubicin encapsulated chitosan alginate nanoparticles and curcumin on multidrug resistant colon cancer cell lines
(University of the Western Cape, 2024)Purpose: Although chemotherapeutic drugs have improved the survival rate of patients diagnosed with colorectal cancer, resistance to chemotherapy frequently leads to therapeutic failure and poor patient outcomes. Multidrug ... -
Effect of Eurycoma longifolia (Tongkat Ali) on the prostate cancer cell line LNCaP
(2013)Eurycoma Longfolia Jack, also known as Tongkat Ali (TA) is a tropical plant belonging to the family of Simaroubaceae is widely distributed in South East Asian countries. The extracts of TA have been proven to have ... -
The effect of flavonoids on the in vitro activity of antibiotics against Staphylococcus aureus
(University of the Western Cape, 2012)Staphylococcus aureus is a Gram-positive coccus belonging to the Stapylococcaeae family. S. aureus causes a wide range of infections that range from skin infections to lifethreatening infections such as pneumonia and ... -
The effect of glycine supplementation on the skeletal muscle properties of captive cheetahs (Acinonyx jubatus)
(University of the Western Cape, 2022)The fastest known land mammal – the cheetah, possesses many anatomical adaptations that enables high-speed running. Current literature regarding the physiological aspects that facilitate their incredible sprinting ability, ... -
The effect of gonadotropin-releasing hormones (GnRH) I & II on sperm motility and acrosome status of the Vervet monkey (Chlorocebus aethiops) in vitro
(University of the Western Cape, 2006)Gonadotropin Releasing Hormone (GnRH) is a hypothalmic decapeptide, which regulates mammalian gonadotropin secretions by binding to specific, high affinity receptors in the pituitary. Two forms of GnRH (GnRH I and GnRH II) ... -
The effect of Libyan date palm pollen and flax seed on general and specific properties of testicular and breast cancer cells
(University of the Western cape, 2016)There is increasing concern worldwide by researchers with regards to the assessing of safety and therapeutic consumption of the plants used in traditional medicine. Date palm pollen (DPP) and flax seed have been used ... -
The effect of maternal nicotine exposure on cell proliferation on the lungs of the offspring
(2013)Tobacco consumption and exposure to tobacco smoke is one of the biggest contributing factors to a growing epidemic of non-communicable diseases (NCDs), primarily cancers, diabetes, cardiovascular and chronic lung diseases ... -
The effect of maternal nicotine exposure on cellular senescence in the lungs of the offspring
(University of the Western Cape, 2012)Several studies conducted in laboratories at the University of the Western Cape has demonstrated an interference with the parenchymal lung tissue of the offspring when exposed to nicotine (smoking cigarettes and/or Nicotine ... -
The effect of maternal nicotine exposure on the alveolar wall composition during the phases of lung development
(University of the Western Cape, 2015)Cigarette smoking is one of the foremost causes of chronic obstructive pulmonary diseases such as emphysema and chronic bronchitis, and although it is the most preventable causes of death, it accounts for approximately 6 ... -
The effect of maternal nicotine, vitamin C and nicotine + vitamin C during gestation and lactation on neonatal lung growth and development
(2009)Maternal smoking is known to cause serious health risks to the unborn child. Recent studies implicate nicotine as the causative factor. Maternal nicotine exposure during pregnancy and lactation interferes with foetal and ... -
The effect of methamphetamine on the blood-testis barrier
(University of the Western Cape, 2018)Introduction The blood-testis barrier (BTB) is formed by tight junctions between adjacent Sertoli cells. The barrier formed by these tight junction helps to create a specialized environment for spermatogenesis and provide ... -
The effect of Nicotine exposure on aspects of liver Carbohydrate metabolism
(University of the Western Cape, 1989)The liver plays an important role in maintaining the blood glucose concentration. In this respect glycogenolysis and gluconeogenesis play an important role. Interference with these pathways may therefore have an effect on ... -
The effect of nigella sativa oil on male reproductive function in male Wistar rats exposed to an obesogenic diet
(University of Western Cape, 2020)Obesity is a growing public health concern globally, particularly in developed countries such as the United States (US). More than 30% of Americans are considered obese. In the past 20 years in America, incidence of ... -
The effect of rooibos and green tea flavnoids on the physiology of TM3 Leydig cells
(University of the Western Cape, 2018)Camellia sinensis (C.sinesis) and Aspalathus linearis (A.linearis) are popular beverages consumed in many countries. Consumption of these plants may protect against cardiovascular disease, neurodegenerative disease, various ... -
The effect of sunitinib on neuroblastoma and glioblastoma cell growth
(University of the Western Cape, 2020)Cancer is a global health catastrophe, with neuroblastoma, the most common solid childhood tumor, and glioblastoma, a deadly brain tumor, being aggressive and unresponsive to current treatment modalities. These tumors are ... -
The effects of carbon-based nanoparticle surface functionalization on immune responses
(University of the Western Cape, 2022)Nano-based technologies are highly desired for the unique properties achieved through size restrictions. Nanoparticles (NPs) achieve a higher surface-to-volume ratio during synthesis. As a result there is a greater rate ... -
The effects of doxorubicin loaded chitosan-alginate nanoparticles on SK-N-BE(2) neuroblastoma cells
(University of the Western Cape, 2022)Cancer is a life-threatening disease and one of the leading causes of death globally. Cancer was thought to be associated with developed countries only but it is increasingly becoming a major health challenge in developing ... -
The effects of Elytropappus rhinocerotis Cass and Pelargonium triste (L.) L'Hèrit on animal health and metabolism
(University of the Western Cape, 2003)Many South Africans use cultural traditions and practices in the management of their health. Elytropappus rhinocerotis is an important medicinal plant, which is widely distributed in regions of South Africa. The objective ... -
The effects of Ethanol and Aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)The blood brain barrier (BBB) is a signaling interface between the blood and the central nervous system (CNS), which prohibits the entry of harmful blood-borne substances into the brain micro-environment, thus maintaining ... -
The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)The blood brain barrier (BBB) is a signaling interface between the blood and the central nervous system (CNS), which prohibits the entry of harmful blood-borne substances into the brain micro-environment, thus maintaining ...