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The effect of flavonoids on the in vitro activity of antibiotics against Staphylococcus aureus
(University of the Western Cape, 2012)
Staphylococcus aureus is a Gram-positive coccus belonging to the Stapylococcaeae family. S. aureus causes a wide range of infections that range from skin infections to lifethreatening infections such as pneumonia and ...
Assessment of raw and treated sewage using in vitro assays
(University of the Western Cape, 2014)
Water scarcity is becoming an increasingly relevant problem for urban centres, especially in Southern Africa. However, water availability is not the only concern for consumers, because water quality is just as relevant. ...
Hyperactivation in human semen and sperm subpopulations by selected calcium modulators
(University of the Western Cape, 2014)
A functional sperm is critical for successful fertilization in order to deliver an intact genome to the site of fertilization. It is often characterized by high motility and normal morphology. Moreover, sperm hyperactivated ...
In vitro effects of rooibos herbal tea (Aspalathus linearis) against methamphetamine on the mouse blood brain barrier
(University of the Western Cape, 2014)
Methamphetamine (MA), also known as ‘Tik’, has detrimental short- and long-term psychological and morphological effects on the central nervous system (CNS). The lipophilic nature of MA allows it to cross the blood-brain ...
Gene expression of xenobiotic metabolising enzymes in rat liver and kidney: differential effects of rooibos and honeybush herbal teas
(2011)
Laboratory studies, epidemiological investigations and human clinical trials indicate
that flavonoids have important effects on cancer chemoprevention and therapy.
Flavonoids may interfere in several steps that lead to ...
The effect of maternal nicotine exposure on cellular senescence in the lungs of the offspring
(University of the Western Cape, 2012)
Several studies conducted in laboratories at the University of the Western Cape has demonstrated an interference with the parenchymal lung tissue of the offspring when exposed to nicotine (smoking cigarettes and/or Nicotine ...
Toxicology and molecular epidemiology of microbes detected in surface water in the Western Cape: The Impact of Informal Settlement
(University of the Western Cape, 2013)
Informal settlements are often implicated in surface water pollution with faecal matter. In most
instances faecal pollution in the associated surface waters persists despite improvements in
sewage removal infrastructure. ...
Production of cytokines in human whole blood after incubation with the nucleocapsid protein of the NL63 Coronavirus
(University of the Western Cape, 2012-11)
The Coronaviridae family consists of RNA viruses within the order Nidovirales. The family is
classified into two genera, namely the corona- and toroviruses. Coronaviruses are enveloped,
single stranded, positive sense ...
Expression of human coronavirus NL63 and SARS-CoV nucleocapsid proteins for antibody production
(University of the Western Cape, 2012)
Human Coronaviruses (HCoVs) are found within the family Coronaviridae (genus, Coronavirus) and are enveloped, single-stranded, positive-sense RNA viruses. Infections of humans by coronaviruses are not normally associated ...