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Evaluation of sperm functionality in non-human primates, focussing on sperm capacitation
(University of the Western Cape, 2019)
The incidence of male infertility is increasing, with up to 50% of infertile males having “unexplained” (idiopathic) infertility. Newly developed molecular techniques have great value in detecting subtle causes of male ...
The Prevalence of Members of the “Red Complex” in Pregnant Women as Revealed by PCR and BANA Hydrolysis.
(University of the Western Cape, 2005)
Increased levels of oestrogen and progesterone during pregnancy may lead to periodontal disease. The anaerobic Gram-negative bacteria called red complex (Porphyromonas gingivalis, Tannerella forsythensis and Treponema ...
The efficiency of drinking water treatment plants in removing immunotoxins
(University of the Western Cape, 2010)
The aim of this study was to evaluate the effectiveness of water treatment processes of two drinking water plants to remove immunotoxins and steroid hormones. Raw and treated drinking water was screened for effects on ...
Synthesis and applications of functionalized pyridinyl imine complexes of palladium
(University of the Western Cape, 2005)
The synthesis and characterization of pyridinyl α-diimine Pd(II) complexes having a functionalized hydrocarbon attached to the imino nitrogen was performed. The catalytic activity of these complexes were then evaluated in ...
Effects of graphene oxide nanoparticles on the immune system biomarkers produced by RAW 264.7
(University of the Western Cape, 2019)
Graphene oxide (GO) is a single carbon layer, oxygen bearing graphene derivative, containing hydroxyl and carboxyl groups. Graphene oxide nanoparticles (GONPs) are promising nanomaterials for a variety of applications such ...
Brine shrimp lethality test and acetylcholine esterase inhibition studies on selected South African medicinal plants
(University of the Western Cape, 2012)
Research into traditional medicines is often conducted in a multidisciplinary approach as motivated by a desire to understand them in as complete a manner as possible,realizing their chemistry, biology and pharmacology. ...
The role of the glutathione system in regulating the levels of ROS neutralisation in the endothelial cells of the blood-brain barrier
(University of the Western Cape, 2017)
Brain endothelial cell types are frequently used as in vitro models to study the
blood-brain barrier (BBB). Oxidative stress (OS) has been reported numerous times
to cause BBB dysfunction which is crucial to the initiation ...
Cloning and expression of human cyclophilin A and its interaction with human coronavirus NL63 nucleocapsid protein
(University of the Western Cape, 2011)
Coronaviridae family is composed of a number of ribonucleic acid (RNA)-containing viruses currently classified into two genera, the coronavirus and torovirus. The family is classified together with the Arteviridae in the ...
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
(University of Western Cape, 2021)
Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ...
Does Olea africana protect the heart against ischemiareperfusion injury?
(2009)
Cardiovascular disease is a major health problem and remains the number one cause of death worldwide. For centuries, medicinal plants have been used in different cultures as medicines for the treatment and control of various ...