| dc.description.abstract | Diabetes has since been a global epidemic; an estimated 5.0 million deaths of diabetes in the world
have been recorded; one in 11 adults have diabetes (415 million); and by 2040, one adult in 10 (642
million) will have diabetes. In Africa, more than two thirds of people with diabetes are undiagnosed,
and 42 million have diabetes in the Sub-Saharan region with 324 877 adult deaths in South Africa (IDF,
2015). The global prevalence (age-standardized) of diabetes has nearly doubled since 1980,rising from
4.7% to 8.5% in the adult population. This reflects an increase associated with risk factors such as
overweight or obese (WHO, 2016). Medicinal plants on the other hand, have played a significant role
in the treatment and prevention of diabetes for centuries. In South Africa, indigenous medicinal plants
have increasingly been used in the treatment of diabetes.
In this study, a new anti-diabetes herbal compound named Jiang Tang 2016 (JT2016), made of three
well researched South African indigenous medicinal plants is investigated for its hypoglycemic effects
in HFD/STZ induced diabetic SD rats. These plants have been used for centuries in the indigenous
system of medicine against various ailments, they are easily accessible, they grow in abundance, and
are economically sustainable.
Aim
The aim of this study was to investigate the hypoglycemic effects and safety of the anti- diabetes
herbal compound, Jiang Tang 2016 (JT2016) in HFD/STZ induced diabetic SD rats | en_US |
