Department of Microbiology
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New Algorithms for EST clustering
(University of the Western Cape, 2000)Expressed sequence tag database is a rich and fast growing source of data for gene expression analysis and drug discovery. Clustering of raw EST data is a necessary step for further analysis and one of the most challenging ... -
The effect of maternal nicotine exposure on rat lung tissue morphology. ' a light and electron microscopic study
(University of the Western Cape, 1991)The infants of women who smoke during pregnancy have a lower birth mass than those born of women who abstain. Animal studies reveal that reduced growth due to maternal nicotine exposure during gestation is accompanied by ... -
The effect of diet on the mucus histochemistry and adjacent histology of the digestive tract in Vervet monkeys.
(University of the Western Cape, 1993)There is a need for defined models of human nutritional disorders partly because serious misconceptions about models are common amongst researchers. Historically a large variety of species has been used including primates, ... -
An investigation of the effects of donor age on some haematological characteristics of the Wistar rat (Rattus Norwegicus)
(University of the Western Cape, 1986)Knowledge of haematological 'normdata', of experimental animals, and the biological variables that affect it is essential in order to recognise variations from the normal. In addition, the haemopoietic system may be ... -
Science text: Facilitating access to physiology through cognition-based reading intervention
(University of the Western Cape, 1995)Reading and understanding science text is the principal means by which students at tertiary level access scientific information and attain scientific literacy. However, understanding and learning from science texts require ... -
The influence of nicotine exposure on the male reproductive system
(University of the Western Cape, 1993)It is well documented that cigarette smoking and nicotine exposure create widespread physiological disorders in humans and animals. The primary tobacco constituent that is responsible for the toxicological consequences ... -
The evaluation of the imp act of interventions by a physiotherapist on intellectually imp aired and physically disabled children and their caregivers in two community groups in peri-urban Cape Town
(University of the Western Cape, 2008)Physiotherapy services for disabled children and their families have conventionally been received at a hospital or school for children with special educational needs in the main towns and cities of South Africa. Community-Based ... -
Identification of novel microRNAs as potential biomarkers for the early diagnosis of ovarian cancer using an in-silico approach
(University of the Western Cape, 2019)Ovarian cancer (OC) is the most fatal gynaecologic malignancy that is generally diagnosed in the advanced stages, resulting in a low survival rate of about 40%. This emphasizes the need to identify a biomarker that can ... -
Synthesis of One-Dimensional TiO2 Nanotube Arrays by Potentiostatic Anodisation
(University of the Western Cape, 2017)TiO2 nanomaterials, in particular nanotubes, are some of the most studied materials, as they are considerably important in technological and biological applications due to their unique electronic properties and biocompatibility. ... -
Parameters affecting the production of fumonisin B1 by fusarium verticillioides in culture
(University of the Western Cape, 2001)Fi1sarium verticillioides is a very important mycotoxin-produeing fungus associated with maize. Fverticillioides produces a group of mycotoxins known as fumonisins under suitable environmental conditions. A series of studies ... -
Reliability of panoramic radiographs to determine the vertical position of the impacted third molar root tip from the inferior alveolar canal
(2013)Nowadays, the availability of radiographic modalities from conventional radiography to more advanced approaches such as medical computed tomography as well as cone beam computed tomography have been useful in providing ... -
Palladium telluride quantum dots biosensor for the determination of indinavir drug
(2013)Indinavir is a potent and well tolerated protease inhibitor drug used as a component of the highly active antiretroviral therapy (HAART) of HIV/AIDS, which results in pharmacokinetics that may be favourable or adverse. ... -
Transcriptional regulatory networks in the mouse hippocampus
(University of the Western Cape, 2007)Neurological diseases are socially disabling and often mortal. To efficiently combat these diseases, a deep understanding of involved cellular processes, gene functions and anatomy is required. However, differential ... -
Functional analysis of the mouse RBBP6 gene using Interference RNA
(University of the Western Cape, 2007)The aim of this thesis was to investigate the cellular role of the mouse RBBP6 gene using the interference RNA (RNAi) gene targeting technology and also to understand the relevance of two promoters for the RBBP6 gene. -
An in vitro study on the immunotoxicity of South African beer
(University of the Western Cape, 2008)Traditionally brewed beers are of cultural and economic importance to many African nations. The presence of mycotoxins in African beer is a topic that needs to be addressed, since most African countries have a climate of ... -
Purification and characterisation of plasmodium falciparum Hypoxanthine phosphoribosyltransferase
(University of the Western Cape, 2007)Malaria remains the most important parasitic disease worldwide. It is estimated that over 500 million infections and more that 2.7 million deaths arising from malaria occur each year. Most (90%) of the infections occur in ... -
Differentials and disparities in the costs of major hospital procedures in South Africa: A structural analysis from the perspective of the supply side
(University of the Western Cape, 2007)The aim of this study was to examine the extent to which providers' practices affect the cost of hospital procedures incurred by patients. The spsecific objective was to explore the magnitude of variations and statistically ... -
Differentiation between Quinolone Resistant and Sensitive Isolates of Campylobacter jejuni by a Multiplex PCR Assay
(University of the Western Cape, 2006) -
Chytridiomycosis in amphibian populations in the Western Cape, South Africa
(University of the Western Cape, 2002)There have been many cases reported of amphibian populations declining. These are often due to anthropogenic factors such as habitat destruction and pollution. However, some eclines have not had an obvious cause and many ... -
Three-dimensional structure of a type III glutamine synthetase by single particle reconstruction
(University of the Western Cape, 2007)This study represents the first structural investigation of any type III glutamine synthetase (GS). The GS, GlnA, from the medically important opportunistic human pathogen Bacteroides fragilis was studied with a view to ...
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