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Now showing items 31-39 of 39
Microscopic analysis of In vitro and In vivo effects of functionalized gold nanoparticles on the liver, kidney, spleen, heart and pancreas of male wistar rats
(University of the Western Cape, 2022)
Nanotechnology represents a promising knowledge based platform that can solve human needs and ailments, especially in cases like cancers, diabetes, antibiotic drug resistances etc. Many metallic nanoparticles are being ...
The effect of glycine supplementation on the skeletal muscle properties of captive cheetahs (Acinonyx jubatus)
(University of the Western Cape, 2022)
The fastest known land mammal – the cheetah, possesses many anatomical adaptations
that enables high-speed running. Current literature regarding the physiological aspects that
facilitate their incredible sprinting ability, ...
Nanostructured immunosensor for low level detection of waterborne cryptosporidium
(University of the Western Cape, 2022)
A major causative agent of gastrointestinal disease is Cryptosporidium, a protozoan
waterborne parasite identified in over 70 countries. Cryptosporidium infection is a
cause of high disease morbidity in children and the ...
Tumour suppression and subdual of cancer (tussc) in elephants: An in vitro study to shed light on Peto’s paradox
(University of the Western Cape, 2022)
Logic would suggest that cancer incidence is related to body mass and longevity. Gigantic
animals such as elephants with a longer lifespan (more lifetime of cell divisions) and a larger
body size (more cells) will have ...
The effects of doxorubicin loaded chitosan-alginate nanoparticles on SK-N-BE(2) neuroblastoma cells
(University of the Western Cape, 2022)
Cancer is a life-threatening disease and one of the leading causes of death globally. Cancer was thought to be associated with developed countries only but it is increasingly becoming a major health challenge in developing ...
In vitro neuroprotective potential of phyllanthin in MPP+- induced toxicity in SH-SY5Y neuroblastoma cells
(University of the Western Cape, 2023)
Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease after Alzheimer’s disease, with an estimated 9 million people projected to be affected worldwide by the year 2030. PD is associated ...
Dexamethasone's impact on LPS-induced inflammation of blood-brain barrier endothelial cells
(University of the Western Cape, 2023)
The blood-brain barrier (BBB) serves as a protective and regulatory barrier between the blood and the brain. Microvascular endothelial cells provide homeostatic regulation of the central nervous system (CNS). BBB integrity ...
The effect of doxorubicin encapsulated chitosan alginate nanoparticles and curcumin on multidrug resistant colon cancer cell lines
(University of the Western Cape, 2024)
Purpose: Although chemotherapeutic drugs have improved the survival rate of patients diagnosed with colorectal cancer, resistance to chemotherapy frequently leads to therapeutic failure and poor patient outcomes. Multidrug ...
The phenomenon of skin lightening among young adults, and the effect of selected plant extracts on tyrosinase and melanogenesis activity
(University of the Western Cape, 2023)
Skin lightening practice refers to the use of skin lightening products to achieve a fairer skin complexion. This is common practice among people of several Asian, North American, South American countries. On the African ...