Browsing Faculty of Natural Science by Title
Now showing items 614-633 of 2560
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Development of nanostructured electrocatalysts using electrochemical atomic layer deposition technique for the direct liquid fuel cells By
(University of Western Cape, 2020)The depletion of fossil fuel resources such as coal and the concern of climatic change arising from the emission of greenhouse gases (GHG) and global warming [1] lead to the identification of the 'hydrogen economy' as one ... -
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ... -
Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ... -
Development of nanotechnology-based therapeutic approaches to treat HIV
(University of the Western Cape, 2012)The rapidly expanding field of nanotechnology has been the focus of many biologists with regard to drug delivery. The ability of nanoparticles to enter cellular compartments makes it possible to explore specific treatment ... -
Development of new dendritic ligands for copper mediated Atom Transfer Radical Polymerization (ATRP) of methyl methacrylate
(University of the Western Cape, 2007)A variety of nitrogen based dendritic ligands have been synthesized and used in copper mediated Atom Transfer Radical Polymerization (ATRP) of MMA. These ligands were derived from the commercially available Generation 1 ... -
Development of novel hypervalent iodine conjugation strategies towards pneumococcal conjugate vaccines
(2013)Invasive pneumococcal disease (IPD), which includes potentially fatal conditions such as meningitis, septicaemia and pneumonia poses a threat in children aged <5 years, pneumonia being the leading cause of child mortality ... -
Development of Open source Laboratory Information Management System (LIMS) For Human Biobanking
(University of the Western Cape, 2018)Biobanks are collections of biological samples and associated data for future use. The day to day activities in a biobank laboratory is underpinned by a laboratory information management system (LIMS). For example, the ... -
Development of palladium nickel/tin metal oxide catalysts on carbon nanotube supports for direct alcohol fuel cells
(University of Western Cape, 2020)Palladium can be used as an anodic catalyst for the alkaline direct alcohol fuel cells (ADAFCs). Palladium has displayed high tolerance towards carbon monoxide (CO) poisoning and high catalytic activity for alcohol oxidation ... -
Development of platino-iridium/ruthenium telluride nanoalloy electrode systems for possible application in ammonia fuel cell
(University of the Western Cape, 2015)South Africa is undergoing a serious consideration of hydrogen economy in an effort to develop safe clean and reliable alternative energy sources for fossil fuels. Ammonia is one of the promising candidates due to its low ... -
Development of polyaniline nanotube electrocatalysts and sesor devices for phenolic-pollutants
(University of the Western Cape, 2007)As a source of life, water is one of the most precious commodities for all living organisms. Water resources are reported to be declining in numbers or the amount of water present and the existing onses are being polluted ... -
Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system
(University of the Western Cape, 2020)Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ... -
Development of Schiff base electrochemical sensors for the evaluation of polycyclic aromatic hydrocarbons in aqueous medium
(University of the Western Cape, 2017)A novel monomer (N,N'-Bis-(1H-pyrrol-2-ylmethylene)-benzene-1,2-diamine-BPPD) was derived from the condensation reaction between o-phenylenediamine and a pyrrole derivative. The monomer was polymerized electrochemically ... -
The development of targeting nanosystems for the treatment of glioblastoma and neuroblastoma tumours
(University of the Western Cape, 2022)Chlorotoxin (CTX) peptide selectively targets glioblastoma multiforme (GB) and neuroblastoma (NB) and has excellent blood-brain barrier permeability. Therefore, CTX is a promising targeting molecule for nanoparticle (NP) ... -
Development of Y-STR genotyping systems suitable for sexual assault cases in South Africa
(University of the Western Cape, 2010)Sexual assault is a significant problem facing the South African society. In this context, efficient but also affordable genotyping systems are needed for positive identification of criminals in incidences of sexual violence. ... -
Development, implementation and evaluation of a diabetes educational outreach inervention for pharmacists
(University of the Western Cape, 2007)Increasing diabetes prevalence rates, poor involvement of and limited knowledge among health care professionals in disease management, and poor implementation of guidelines are barriers to quality diabetes care. This thesis ... -
The development, implementation and evaluation of an integrated framework for undergraduate pharmacy education in maternal and child health at the University of the Western Cape
(University of the Western Cape, 2022)The high rate of maternal and child mortality is a global health concern. Nationally, it is one of South Africa’s quadruple disease burdens. The Sustainable Development Goal 3, 2030 targets related to maternal and child ... -
The development, optimisation and evaluation of molecular methods to diagnose abalone tubercle mycosis (ATM) caused by Halioticida Noduliformans in South African abalone, Haliotis Midae
(University of the Western Cape, 2012)Land-based abalone aquaculture in South Africa started in the early 1990s and is based on the local species Haliotis midae. This industry expanded with great success over the last decade. In 2006 abalone exhibiting typical ... -
Dexamethasone's impact on LPS-induced inflammation of blood-brain barrier endothelial cells
(University of the Western Cape, 2023)The blood-brain barrier (BBB) serves as a protective and regulatory barrier between the blood and the brain. Microvascular endothelial cells provide homeostatic regulation of the central nervous system (CNS). BBB integrity ... -
The diet and feeding ecology of the brown house snake, Boaedon capensis
(University of the Western Cape, 2022)African brown house snakes (Boaedon capensis) are widely thought to be dietary specialists that predominantly consume rodents. Given their ubiquitous distribution, these snakes potentially play an important role in ... -
The diet and feeding of the pelagic goby, sufflogobius bibarbatus, off Namibia
(University of the Western Cape, 2009)The general diet of Sufflogobius bibarbatus in the northern Benguela upwelling ecosystem was investigated from gut content analysis in two separate studies. The first study was conducted over two 48 h diel sampling stations ...