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Evaluating cape honey bee sperm quality and the in vitro effect of miticides on sperm functionality and structure
(University of Western Cape, 2021)
Apis mellifera (honey bees) are essential pollinators and thus considered a keystone species. Reproductive success is therefore important to the survival of the species, with drone sperm quality playing a vital role in ...
The impact of nanoparticles on the proteome of cultured human cells
(2021)
Living organisms are constantly being exposed to nanoparticles (NPs) in the environment via air,
water, soil. Routes of exposure are usually in the form of industrial, occupational exposure, as well
as therapeutic ...
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
(University of Western Cape, 2021)
Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ...
The effects of silver nanoparticles on the expression of protein biomarkers of cell stress, apoptosis and inflammation by the human liver cancer cell line, HepG2
(University of Western Cape, 2021)
Nanoscience is the study of phenomena and objects at the nanoscale (around 1-100 nm), socalled
nanomaterials. These nanomaterials exhibit novel properties that are often very
different to those of the bulk materials used ...
The effects of titanium oxide nanoparticles on cultured cells and the immune system
(University of Western Cape, 2021)
Engineered nanomaterials derived from various bulk materials are being developed in ever larger quantities and with very diverse chemical compositions. The physical and chemical properties of the smaller nanoparticles are ...
The characterisation of human coronavirus nl63 proteins
(University of Western Cape, 2021)
Human Coronavirus NL63 (HCoV-NL63) is one of seven coronaviruses (CoVs) that cause respiratory disease in the global population. The Membrane (M) and Nucleocapsid (N) proteins are part of the core CoV-structural proteins, ...
Cell culture biomarkers for monitoring of wastewater pollutants
(University of the Western Cape, 2021)
Wastewater is normally composed of a mixture of pollutants. The type and composition of pollutants in a particular wastewater depend on the source of origin. The source and characteristics of a particular wastewater determine ...
Optimizing embryo culture conditions and spent culture media analysis as predictors of embryo quality and pregnancy
(University of the Western Cape, 2021)
The aim of this thesis is first, to evaluate various culture conditions to improve embryo development, and secondly, to analyze spent culture media for any biomarkers that may be predictive of embryo health. Single-step ...
The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro
(University of Western Cape, 2021)
The testes play a central role in the male reproductive system, as they represent the sites of male sex steroidogenesis and of spermatogenesis. Leydig cells, located at the testicular interstitium, produce predominantly ...
Investigating hypoglycaemic effects and safety of the herbal Product – JT2016 in vivo study
(University of the Western Cape, 2021)
Diabetes has since been a global epidemic; an estimated 5.0 million deaths of diabetes in the world
have been recorded; one in 11 adults have diabetes (415 million); and by 2040, one adult in 10 (642
million) will have ...