Browsing Magister Scientiae - MSc (Medical BioSciences) by Issue Date
Now showing items 41-60 of 159
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Does maternal nicotine exposure during gestation and lactation change the oxidant-antioxidant status of the lungs of the offsprings and is tomato juice protecting the lungs of the offsprings?
(University of the Western Cape, 2009)Nicotine exposure to the fetus through tobacco smoking or nicotine replacement therapy during the whole period of gestation and lactation causes diverse effects on fetal and neonatal lung development, integrity and maturation ... -
Does Olea africana protect the heart against ischemiareperfusion injury?
(2009)Cardiovascular disease is a major health problem and remains the number one cause of death worldwide. For centuries, medicinal plants have been used in different cultures as medicines for the treatment and control of various ... -
Cloning of Human Coronavirus NL-63 ORF3, M and E genes for antibody production
(University of the Western Cape, 2010)Human Coronavirus NL-63 is a respiratory virus with a high incidence rate, causing mild respiratory infections in children under the age of 18. The outbreak of Sever Acute Respiratory Syndrome (SARS) in 2003 sparked increased ... -
The efficiency of drinking water treatment plants in removing immunotoxins
(University of the Western Cape, 2010)The aim of this study was to evaluate the effectiveness of water treatment processes of two drinking water plants to remove immunotoxins and steroid hormones. Raw and treated drinking water was screened for effects on ... -
Gene expression of xenobiotic metabolising enzymes in rat liver and kidney: differential effects of rooibos and honeybush herbal teas
(2011)Laboratory studies, epidemiological investigations and human clinical trials indicate that flavonoids have important effects on cancer chemoprevention and therapy. Flavonoids may interfere in several steps that lead to ... -
Cloning and characterization of the human coronavirus NL63 nucleocapsid protein
(University of the Western Cape, 2011)The human coronavirus NL63 was discovered in 2004 by a team of researchers in Amsterdam. Since its discovery it has been shown to have worldwide spread and affects mainly children, aged 0-5 years old, the immunocompromised ... -
Cloning and expression of human cyclophilin A and its interaction with human coronavirus NL63 nucleocapsid protein
(University of the Western Cape, 2011)Coronaviridae family is composed of a number of ribonucleic acid (RNA)-containing viruses currently classified into two genera, the coronavirus and torovirus. The family is classified together with the Arteviridae in the ... -
Comparison between chemical and tissue culture methods to monitor environmental estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
The in vitro effects of pure and street methamphetamine on the proliferation and cell cycle of mouse brain endothelial (bend5) cells
(2012)The blood-brain barrier (BBB) is an interface between the brain parenchyma and the circulating system. This barrier plays a vital role in protecting the CNS by restricting free paracellular diffusion of molecules from the ... -
The in vitro effects of nicotine and selected antibiotics, tunicamycin and thapsigargin on human Breast carcinoma (mcf-7) cells.
(University of the Western Cape, 2012)Cancer is defined as the abnormal growth of genetically mutated or perturbant cells. Nicotine is a known cancer promoter and an apoptotic suppressor. This alkaloid acts on the nicotinic acetylcholine receptors which affects ... -
Immunohistochemical analysis of a panel of human and murine markers on xenografted human vaginal mucosa: a comparative study
(University of the Western Cape, 2012)Athymic nude mouse models have been extensively used to study biological behaviour of normal and diseased human tissues. In such models, immune-deficient mice act as hosts for cysts constructed from human material. A unique ... -
The effect of flavonoids on the in vitro activity of antibiotics against Staphylococcus aureus
(University of the Western Cape, 2012)Staphylococcus aureus is a Gram-positive coccus belonging to the Stapylococcaeae family. S. aureus causes a wide range of infections that range from skin infections to lifethreatening infections such as pneumonia and ... -
The effect of maternal nicotine exposure on cellular senescence in the lungs of the offspring
(University of the Western Cape, 2012)Several studies conducted in laboratories at the University of the Western Cape has demonstrated an interference with the parenchymal lung tissue of the offspring when exposed to nicotine (smoking cigarettes and/or Nicotine ... -
Expression of human coronavirus NL63 and SARS-CoV nucleocapsid proteins for antibody production
(University of the Western Cape, 2012)Human Coronaviruses (HCoVs) are found within the family Coronaviridae (genus, Coronavirus) and are enveloped, single-stranded, positive-sense RNA viruses. Infections of humans by coronaviruses are not normally associated ... -
Prevalence and characterization of Gardnerella vaginalis in pregnant mothers with a history of preterm delivery
(University of the Western Cape, 2012)Risk factors such as intrauterine and vaginal infection put pregnant women at risk for delivering preterm. Bacterial vaginosis (BV) is a polymicrobial clinical syndrome commonly diagnosed in women of reproductive age, with ... -
Investigations on the in vitro effects of aqueous Eurycoma longifolia Jack extract on male reproductive functions
(University of Western Cape, 2012)Introduction: Eurycoma longifolia (Tongkat Ali; TA) is a Malaysian shrub used to treat various illnesses including male infertility. Considering that TA is also used to improve male fertility and no report regarding ... -
Brine shrimp lethality test and acetylcholine esterase inhibition studies on selected South African medicinal plants
(University of the Western Cape, 2012)Research into traditional medicines is often conducted in a multidisciplinary approach as motivated by a desire to understand them in as complete a manner as possible,realizing their chemistry, biology and pharmacology. ... -
Molecular genetics: strategies to identify congenital cataract genes in captive-bred Vervet monkeys
(University of the Western Cape, 2012)The present study describes molecular aspects of inherited congenital cataract in captive-bred Vervet monkeys. Congenital cataracts are lens opacities that are present at birth or soon after birth and include hereditary ... -
Comparison between chemical and tissue culture methods to monitor environmental Estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ...