Browsing by Subject "Gold nanoparticles"
Now showing items 1-20 of 27
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Antimicrobial, anticancer and catalytic activities of green synthesized Avocado seed extract-gold nanoparticles
(University of the Western Cape, 2019)Nature through billions of years of trial and error has produced an immeasurable amount of natural systems like plants, birds and animals. The intelligence of nature is hidden in these natural systems and researchers are ... -
A baseline evaluation of the cytotoxicity of gold nanoparticles in different types of mammalian cells for future radiosensitization studies
(University of the Western Cape, 2020)Recently nanoparticles (NPs) have been introduced and used in combination with therapeutic approaches to develop nanotechnology-enabled medicine. These nanostructures allow for the exploitation of the physiochemical ... -
A baseline evaluation of the cytotoxicity of gold nanoparticles in different types of mammalian cells for future radiosensitization studies
(University of the Western Cape, 2020)Recently nanoparticles (NPs) have been introduced and used in combination with therapeutic approaches to develop nanotechnology-enabled medicine. These nanostructures allow for the exploitation of the physiochemical ... -
Biogenic synthesis of gold nanoparticles using red and green pear fruit extracts
(University of the Western Cape, 2019)There has been a growing interest in the design of biocompatible and environmentally affable nanoparticles (NPs) among scientists to develop novel and safe biomaterials for use in various biomedical applications. This can ... -
Developing a lateral flow device for the detection of novel breast cancer biomarkers
(University of the Western Cape, 2023)Breast cancer is the most prevalent malignancy and one of the leading causes of death in women worldwide. Delayed diagnosis of breast cancer greatly reduces the effectiveness of treatment and is considered one of the major ... -
Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ... -
Electrochemical actuation potential of diaminophenazine linked pyrrole derivatives
(2013)A novel monomer (Phenazine-2,3-diimino(pyrrole-2-yl)–PDP) derived from the condensation reaction between 2,3-diaminophenazine and a pyrrole derivative has been synthesized as a hinge molecule in the design of a zig-zag ... -
Electrochemical poly(ProDOT) dendritic DNA aptamer biosensor for signalling interferon gamma (IFN-ɣ) TB biomarker
(University of the Western Cape, 2017)Tuberculosis (TB) is an infectious disease that, despite all efforts devoted towards its eradication, remains a threat to many countries including South Africa. Current diagnostic assays do offer better performance than ... -
Evaluation of cytotoxic activity of gold nanoparticles naturally synthesised from South African indigenous medicinal plant extracts
(University of the Western Cape, 2018)Nanotechnology has emerged as a promising field in the quest to address health conditions. Green nanotechnology is a fairly new branch of nanotechnology, which aims to produce and utilize nanomaterials in a way that is ... -
Frequency and voltage-modulated electrochemical aflatoxin B1 immunosensor systems prepared on electroactive organic polymer platforms
(University of the Western Cape, 2008)In the presented work, immunosensors for detection of Aflatoxin B1 based on different immobilization platforms were studied. Synthesis of an electroactive hydrogel was also carried out. Aflatoxins are a group of mycotoxins ... -
Frequency and voltage-modulated electrochemical aflatoxin b1immunosensor systems prepared on electroactive organic polymer platforms
(2008)In the presented work, immunosensors for detection of Aflatoxin B1 based on different immobilization platforms were studied. Synthesis of an electroactive hydrogel was also carried out. Aflatoxins are a group of mycotoxins ... -
Green synthesis and characterization of gold nanoparticles from South African plants and their biological evaluations
(University of the Western Cape, 2019)The field of nanotechnology continues to offer solutions for biotechnologists whose target is to improve the quality of life by finding new therapies to combat diseases. Gold nanoparticles (AuNPs) have been showing great ... -
Impedimetric and electrode kinetic dynamics of DNA aptamer nanobiosensors for estrogeneous endocrine disruptors
(University of the Western Cape, 2011)In this work, DNA aptamer biosensor systems were developed for the detection of l7p-estradiol - an estrogeneous endocrine disrupting chemical (EDC). Endocrine disrupting chemicals are group of compounds that impact negatively ... -
Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
(University of the Western Cape, 2023)The incidence and prevalence of obesity and its related diseases has nearly tripled and is increasing at an alarming rate worldwide. Several modern methods for the management and treatment of obesity are available, with ... -
Microfluidic graphenised-paper electroanalytical devices (μGPED) for adsorptive cathodic stripping voltammetric detection of metal contaminants
(University of the Western Cape, 2017)The need for clean, non-toxic drinking water supplies, free of pollutants and metal contamination is vital in impoverished areas and the developing world alike. With this in mind, the development of accurate, inexpensive, ... -
Microscopic analysis of In vitro and In vivo effects of functionalized gold nanoparticles on the liver, kidney, spleen, heart and pancreas of male wistar rats
(University of the Western Cape, 2022)Nanotechnology represents a promising knowledge based platform that can solve human needs and ailments, especially in cases like cancers, diabetes, antibiotic drug resistances etc. Many metallic nanoparticles are being ... -
Nanocomposite immunosensor for anti-transglutaminase antibody
(University of the Western Cape, 2009)Coeliac disease (CD) is a gluten intolerance condition that results in the flattening of the villi, which line the bowel. It is the most common cause of malabsorption of food nutrients. This inability to absorb sufficient ... -
Nanoformulation of Artemisia afra and its potential biomedical applications in type 2 diabetes
(University of Western Cape, 2019)Current research classifies Type 2 diabetes as most prevalent non-communicable diseases in South Africa. Approximately 285 million people are affected globally with an expected increase to 595 million by the year 2035. ... -
Nanostructured immunosensor for low level detection of waterborne cryptosporidium
(University of the Western Cape, 2022)A major causative agent of gastrointestinal disease is Cryptosporidium, a protozoan waterborne parasite identified in over 70 countries. Cryptosporidium infection is a cause of high disease morbidity in children and the ... -
Novel gold nanoparticles of drought tolerance enabler GYY4137
(University of the Western Cape, 2019)Different nanoparticles have the ability to improve plant tolerance to drought stress. In the study we report for the first time novel morpholin-4-ium 4-methoxyphenyl (morpholino) phosphinodithioate capped- gold nanoparticles ...