Browsing Magister Scientiae - MSc (Bioinformatics) by Author "Gamieldien, Junaid"
Now showing items 1-4 of 4
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Development of a simple artificial intelligence method to accurately subtype breast cancers based on gene expression barcodes
Esterhuysen, Fanechka Naomi (University of the Western Cape, 2018)INTRODUCTION: Breast cancer is a highly heterogeneous disease. The complexity of achieving an accurate diagnosis and an effective treatment regimen lies within this heterogeneity. Subtypes of the disease are not simply ... -
Integrating regulatory and methylome data for the discovery of clear cell Renal Cell Carcinoma (ccRCC) variants
Calvert-Joshua, Tracey (University of the Western Cape, 2015)Kidney cancers, of which clear cell renal cell carcinoma comprises an estimated 70%, have been placed amongst the top ten most common cancers in both males and females. With a mortality rate that exceeds 40%, kidney cancer ... -
“An investigation into the MicroRNA-gene interactions involved in the pathogenesis of systemic lupus erythematosus”
Pitts, Stephanie Julia (University of the Western Cape, 2015)Systemic lupus erythematosus is a chronic, inflammatory disease characterised by the production of autoantibodies which target particularly the nuclear components of multiple cell types throughout the body. MicroRNA’s have ... -
Normalization and statistical methods for crossplatform expression array analysis
Mapiye, Darlington S (University of the Western Cape, 2012)A large volume of gene expression data exists in public repositories like the NCBI’s Gene Expression Omnibus (GEO) and the EBI’s ArrayExpress and a significant opportunity to re-use data in various combinations for novel ...