Browsing School of Pharmacy by Title
Now showing items 95-114 of 228
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Evaluation of selected polycyclic compounds as resistance modulators in Mycobacterium tuberculosis
(University of the Western Cape, 2022)Progressive development of resistance to various chemotherapeutic agents used in the management of infectious diseases presents a serious problem in global public health. Increasing levels of antimicrobial resistance in ... -
Evaluation of the anticonvulsant activity of Elytropappus rhinocerotis (L.f) Less
(University of the Western Cape, 2016)M.Pharm thesis, Discipline of Pharmacology, School of Pharmacy, University of the Western Cape. Epilepsy is a worldwide neurological disorder which is also prevalent in South Africa. Herbal medicines, besides orthodox ... -
Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta Graveolens L. in mice and rats
(University of the Western Cape, 2012)Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta graveolens L. in mice and rats FIRDOWS LOONAT M. Pharm. Pharmaceutical Sciences thesis: School of Pharmacy, University of the Western ... -
An Evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, Traditional Medicinal Plants used in the Western Cape
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifolia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
An evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifulia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
Evaluation of the effect of polyethylene glycol incorporation on the performance of poly(lactic-co-glycolic acid) nanoparticles
(University of the Western Cape, 2016)Nanoparticle drug delivery is challenged by the binding of proteins in blood which result in their rapid removal from the circulatory system. Nanoparticles engineered to delay protein binding have shown to have extended ... -
Evaluation of the pulmonary effects of the traditionally prepared Artemisia afra steam inhalation and nebulized aqueous extract and the possible involvement of flavonoid luteolin
(University of the Western Cape, 2006)Artemisia afra is a popular medicinal plant traditionally used to treat respiratory conditions such as asthma, bronchitis etc., most frequently as a steam inhalation. The effectiveness of this steam inhalation, its active ... -
An evaluation of western herbal complementary medicine labelling in South Africa, to determine whether the product labelling information complies with established herbal monographs and whether it meets local regulatory requirements
(University of the Western Cape, 2015)Medicines (CMs) are widely available to the South African public. However, CMs have not yet been evaluated by the Medicines Control Council (MCC). The MCC has published new guidelines for the regulation of CMs, with which ... -
Examining the inventory management of antiretroviral drugs at community health centres in the cape metropole, Western Cape
(2013)South Africa is faced with a high number of people living with HIV/AIDS, and subsequently a great need to access quality medicines for improving patient therapeutic outcomes. Antiretroviral drugs (ARVs) require rigid, ... -
Expanding presumptive male partner management of sexually transmitted infections (STIs) to Western Cape, South African community retail pharmacies
(University of the Western Cape, 2007)The effect of industrialisation has thrust the pharmaceutical profession into a clinical paradigm where the approcah to pharmaceutical decisions is more disease and patient orientated. Consequently, South African community ... -
Exploration of the training/educational background and the roles of regulatory affairs associates/officers in selected South African based pharmaceutical companies in Gauteng province
(University of Western Cape, 2021)Regulatory Affairs (RA), within the pharmaceutical business, could be a profession that covers different registration parameters of a pharmaceutical product. This is a profession that was developed to protect the public ... -
An exploratory study of the problem of training and skills development in the public health sector: The case of two district hospitals in the Limpopo province
(University of the Western Cape, 2022)Public health sectors across the globe are usually faced with challenges of adopting creative ways to improve performance and service delivery in the form of investing in employee skills development and training. During ... -
Exploring a participatory multi-stakeholder engagement approach to address chronic medicine use
(University of the Western Cape, 2023)Background: In South Africa, chronic diseases (CD) fall into the quadruple burdens of diseases. In 2018 the World Health Organization (WHO) reported that chronic diseases were responsible for more than fifty percent of ... -
Exploring the factors influencing the sustainability of mobile clinics for the delivery of the expanded programme on immunisation to the rural areas of the Northern Cape.
(University of Western Cape, 2021)The Northern Cape province has not been able to achieve the 90% immunization target recommended for South Africa’s expanded programme on immunisation (EPI). The situation has been attributed to the lack of access to EPI ... -
Factors affecting the pharmacokinetics of vancomycin in children admitted to the intensive care unit (icu) of the Red Cross War Memorial Children's Hospital (RCWMCH).
(University of the Western Cape, 2023)Vancomycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminal end of cell wall precursor units preventing the elongation and cross-linkage of the ... -
Feasibility of an internationally recognized conformitè europëenne equivalent mark for medical devices in africa: a review of current literature
(University of the Western cape, 2024)Medical devices are crucial to health systems and are critical to addressing the disease burden of African countries. In light of the importance of diagnosis and surgical intervention in healthcare, medical devices such ... -
The formulation and characterisation of corticosteroid loaded Ethosomes for topical delivery
(University of the Western Cape, 2020)Background/Introduction: Atopic dermatitis (AD) is one of the most prevalent diseases worldwide. It is a rapidly growing field of study with several research avenues to explore its pathophysiology and to find innovative ... -
The formulation and evaluation of indomethacin tablets
(University of the Western Cape, 1998)The overall objective of this research is to attempt to produce, by direct compression, indomethacin tablets which have good dissolution characteristics and an improved bioavailability profile, when compared to the capsule ... -
Formulation and evaluation of polymeric micelles for improved oral delivery of tenofovir disoproxil fumarate and zidovudine using poly-lactic-co-glycolic acid nanoparticles
(University of the Western Cape, 2018)Background: Tenofovir disoproxil fumarate (TDF) and Zidovudine (AZT) are both nucleotide and nucleoside analogue reverse transcriptase inhibitors (NtRTIs and NRTIs), respectively. They are used for the management and ... -
The formulation and evaluation of rapid release tablets manufactured from Artemisia Afra plant material
(University of the Western Cape, 2004)Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing ...