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Functional analysis of miRNA regulated genes in prostate cancer as potential diagnostic molecules
(University of the Western Cape, 2016)
Prostate Cancer is the leading cause of cancer-related death in males in the Western world. It is a common biological disease originating from the reproductive system of the male namely, the prostate gland, usually in older ...
Antimicrobial, anticancer and catalytic activities of green synthesized Avocado seed extract-gold nanoparticles
(University of the Western Cape, 2019)
Nature through billions of years of trial and error has produced an immeasurable amount of
natural systems like plants, birds and animals. The intelligence of nature is hidden in these
natural systems and researchers are ...
Increasing ethanol tolerance through the heterologous expression of the geobacillus thermoglucosiadius heat-shock proteins (GroEL/GroES) in an escherichia coli host
(University of the Western Cape, 2012)
Due to economic and environmental concerns associated with use of fossil fuels, humanity is seeking alternative fuels. Ethanol is one of the alternative fuels produced commercially. Current ethanol production technologies ...
The assessment of the bactericidal effect of green synthesized silver nanoparticles against a panel of infectious microorganisms
(University of the Western Cape, 2016)
The emergence of multiple drug resistant microorganisms poses a major threat to human life. These microorganisms have made the currently used antibiotics ineffective and therefore continue to thrive. Therefore, there is a ...
Characterisation of a DNA ligase from an Antarctic metagenomic library
(University of the Western Cape, 2011)
A metagenomic gene library prepared from soil found beneath a mummified seal carcass in the Miers Valley, Antarctica, suggests an environment rich in uncharacterised biodiversity including enzymes with possible application ...
Investigating the functional interaction of transcription regulator CarD of Mycobacterium tuberculosis with Ribonucleic Acid Polymerase
(University of the Western Cape, 2014)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ...
Eukaryotic diversity of miers valley hypoliths
(University of the Western Cape, 2012)
The extreme conditions of Antarctic desert soils render this environment selective towards a diverse range of psychrotrophic microbial communities. Cracks and fissures in translucent quartz rocks permit an adequate amount ...
Development of microsatellite (SSR) marker multiplexes for future construction of a genetic linkage map for pear (Pyrus communis L.)
(University of the Western Cape, 2012)
Recent advances in the field of plant genetics and application of molecular technologies has lead to greater understanding of various crop genomes and their organization.The applications of these techniques include molecular ...
Isolation and preliminary characterization of bacteriophages of thermophilic Bacillus and Geobacillus species
(University of the Western Cape, 2015)
Thermophilic bacteriophages provide simple model systems for understanding
biochemical and biological adaptation mechanisms at elevated temperatures. The
essential objectives of this study were to characterise the ...
Functional characterisation of a novel ferulic acid esterase from malawian hot spring metagenome
(2011)
There has been a decline in the global fossil fuel reserves, due to an increasing demand for petroleum. Biofuels can be used as an alternative source of energy whereby biomass is converted to liquid fuels such as bioethanol. ...