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Electrochemical dynamics of cytochrome P450-3A4 isoenzyme biosensor for protease inhibitor antiretroviral drug
(2010)
This thesis firstly reports on the development and characterization of reagent-less and cobalt(III) sepulchrate[Co(Sep)³⁺] mediated biosensor platforms (biosensor platform 1 and biosensor platform 2), with human recombinant ...
Evaluation of the leachate chemistry and contaminants attenuation in acid mine drainage by fly ash and its derivatives
(University of the Western Cape, 2006)
The mining industry in South Africa has a huge potential to impact negatively on the environment. Negative impacts include generation of reactive tailings and acid mine drainage (AMD). AMD is highly acidic (pH 2-4), ...
The synthesis and evaluation of potential anti-Mycobacterium tuberculosis and apoptotic agents
(University of the Western Cape, 2007)
Tuberculosis (TB) and Cancer are among the most devastating and therapeutically challenging diseases that need to be addressed in South Africa today. The development of muti-drug resistance in TB causing bacteria, Mycobacterium ...
Characterization and chemical speciation modelling of saline effluents at Sasol Synthetic Fuels Complex-Secunda and Tukuta power station
(University of the Western Cape, 2009)
The study shows conclusively that brine composition and concentration is highly variable at these South African power utilities and processes such as RO, contact with ash and CO2 ingress can have an impact upon the overall ...
Phytochemical study of Rhoicissus tomentosa
(University of the Western Cape, 2008)
This investigation focused on Rhoicissus tomentosa, belonging to the family, Vitaceae in an attempt to assess the phytochemistry of this plant which is widely used by traditional healers in South Africa to ensure the safe ...
The application of high capacity ion exchange absorbent material, synthesized from fly ash and acid mine drainage, for the removal of heavy and trace metals from secondary co-disposed process waters
(University of the Western Cape, 2005)
The objective of this study was to investigate the feasibility of the application of low cost high capacity inorganic ion exchange material, synthesized form collected fly ash and acid mine drainage solid residues, for the ...
The extraction, purification and evaluation of compounds from the leaves of Leonotis Leonorus for anticonvulsant activity
(University of the Western Cape, 2002)
The aim of this study is to isolate and evaluate the anticonvulsant components from the leaves of Leonotis leonorus (L) R.aR. and to see if there is any change in activity with the origin of the plant material and I or the ...
Development of a gas chromatographic technique for the analysis of some groundwater contaminants from fuel leaks and its application in a site-specific study
(University of the Western Cape, 2009)
This study focuses on the development of a Direct Aqueous Injection Gas Chromatographic method with Flame Ionization Detection (DAI-GC/FID) for the analysis of MTBE and TBA. The analytical method was then applied in a site ...
Chemical isolation and electro-chemical characterization of antidiabetic compounds from selected South African lamiaceae plant species
(University of the Western Cape, 2020)
Diabetes mellitus (DM), being one of the most common metabolic disorders with an elevated morbidity and mortality rate around the world. It is characterised by deficiency in insulin secretion or degradation of secreted ...
Long-range transport clusters, fine particulate matter (PM2.5) and soot concentrations of air masses in Cape Town, South Africa
(University of the Western Cape, 2018)
Ambient air pollution is the biggest environmental threat to human health. According to the World Health Organisation (WHO), ambient air pollution kills millions of people worldwide every year. Airborne particulate matter ...