Browsing Department of Biotechnology by Author "Sewell, Bryan Trevor"
Now showing items 1-3 of 3
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The feasibility of high resolution, three-dimensional reconstruction of metal-coated surfaces in structural biology
Woodward, Jeremy David (2006)Life is an emergent property of a complex network of interacting cellular-machines. Three-dimensional (3D), cellular structure captured at supra-atomic resolution has the potential to revolutionise our understanding of the ... -
Human testis angiotensin-converting enzyme: crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis
Watermeyer, Jean Margaret (University of the Western Cape, 2004)Human angiotensin-converting enzyme (ACE) is a key enzyme in the regulation of blood pressure via the renin-angiotensin and kallikrein-kinin systems. A number of orally active drugs have been developed over the years ... -
The structure of the nitrilase from Rhodococcus Rhodochrous J1: homology modeling and three-dimensional reconstruction
Thuku, Robert Ndoria (University of the Western Cape, 2006)The nitrilases are an important class of industrial enzymes that are found in all phyla. These enzymes are expressed widely in prokaryotes and eukaryotes. Nitrilases convert nitriles to corresponding acids and ammonia. ...