Browsing Department of Biotechnology by Title
Now showing items 1-20 of 345
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3,3' Diindolylmethane mediated signalling and its role in Brassica napus L. responses to vanadium
(University of the Western Cape, 2016)Anthropogenic activities such as mineral mining, improper watering practices, and the use of heavy metal contaminated fertilizers have caused an influx of heavy metals into arable lands. These heavy metals may have a ... -
3,3'-diindolylmethane improves drought tolerance of Zea mays through enhancing antioxidant activity
(University of the Western Cape, 2018)Maize is one of the most abundantly produced cereals and contributes to about 40% of the global cereal production. This figure will have to increase in order to feed the ever-growing human population. One of the major ... -
A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting
(University of the Western Cape, 2018)The objective of this study is to deduce paternal ancestry using ancestry informative single nucleotide polymorphisms (SNPs) by means of High Resolution Melting (HRM). This was completed by producing a multiplex system that ... -
Actinobacterial and archaeal diversity in lake Magadi, Kenya
(University of the Western Cape, 2013)Microorganisms of the class Actinobacteria and domain Archaea are interesting from a biotechnological perspective owing to their metabolic attributes as producers of secondary metabolites and resilience under harsh ... -
Actinobacterial diversity of the Ethiopian Rift Valley lakes
(University of the Western Cape, 2011)The class Actinobacteria consists of a heterogeneous group of filamentous, Gram-positive bacteria that colonise most terrestrial and aquatic environments. The industrial and biotechnological importance of the secondary ... -
An investigation of the zinc binding characteristics of the RING finger domain from the human RBBP6 protein using heteronuclear NMR spectroscopy.
(University of the Western Cape, 2007)Retinoblastoma binding prot ein 6 (RBBP6) is a 250 kDa human splicing-associated protein that is also known to interact with tumour suppresso r proteins p53 and pRb and to mediate ubiquitination of p53 via its ... -
Analysis of ammonia-oxidizing bacteria associated with the roots of Proteaceae plant species in soils of Fynbos ecosystem
(University of the Western Cape, 2005)The major objective of this study was to investigate soil ammonia-oxidizing bacterial diversity and composition associated with plant roots of Proteaceae plants and to compare it with non-plant associated soil. -
Analysis of ammonia-oxidizing bacteria associated with the roots of Proteaceae plant species in soils of Fynbos ecosystem
(University of the Western Cape, 2005)Molecular methods were used to investigate the microbial diversity and community structure of ammonia-oxidizing bacteria (AOB) associated with the roots of the Proteaceae plant family. The identification of ammonia ... -
Analysis of the early events in the interaction between Venturia inaequalis and the susceptible Golden Delicious apple (Malus x domestica Borkh.)
(University of the Western Cape, 2014)Apple (Malus x domestica) production in the Western Cape, South Africa, is one of the major contributors to the gross domestic product (GDP) of the region. The production of apples is affected by a number of diseases. One ... -
Analysis of the proteome of red and green leaf phenotypes of 'Bon Rouge' pear trees \trus communrls L. by 2-dimensional gel electrophoresis
(University of the Western Cape, 2007)The 'Bon Rouge' pear is a red pear cultivar derived from a rare, spontaneous bud mutation which occurred on the green pear 'William's Bon Chretien' (Bartlett). 'Bon Rouge' pear cultivar was observed to be reverting back ... -
Analysis, expression profiling and characterization of hsa-miR-5698 target genes as putative dynamic network biomarkers for prostate cancer: a combined in silico and molecular approach
(University of the Western Cape, 2019)2018, the International Agency for Research on Cancer (IARC) estimated that prostate cancer (PCa) was the second leading cause of death in males worldwide. The number of deaths are expected to raise by 50 % in the next ... -
Ancient Genes in Cancer Gene Expression?
(University of the Western Cape, 2004)Backsround: The Cancer/testis (CT) antigens are a division of germ cell specific genes not expressed in somatic cells, exceptions being placental cells and 20Vo - 4OVo of cancer types. The aptitude of CT antigens to elicit ... -
The antimicrobial activity of zinc oxide nanoparticles synthesized with plant extracts against Staphylococcus aureus
(University of the Western Cape, 2019)Nanoparticles using a green synthesis production method is of increasing interest for biomedical applications. Zinc oxide is currently used in medicinal and cosmetic formulations, and zinc oxide nanoparticles have potential ... -
Antimicrobial, anticancer and catalytic activities of green synthesized Avocado seed extract-gold nanoparticles
(University of the Western Cape, 2019)Nature through billions of years of trial and error has produced an immeasurable amount of natural systems like plants, birds and animals. The intelligence of nature is hidden in these natural systems and researchers are ... -
Aptamer selection against GFRa1 for its application in the prognosis of breast cancer
(University of the Western Cape, 2019)Breast cancer is the second most common cancer amongst South African women. Despite ongoing efforts to combat breast cancer, current prognostic and/or therapeutic monitoring methods are limited since very little improvement, ... -
The assessment of the bactericidal effect of green synthesized silver nanoparticles against a panel of infectious microorganisms
(University of the Western Cape, 2016)The emergence of multiple drug resistant microorganisms poses a major threat to human life. These microorganisms have made the currently used antibiotics ineffective and therefore continue to thrive. Therefore, there is a ... -
An assessment of the dietary intake of pregnant women in the West Coast / Winelands region, Western Cape Province: relation to low birth weight
(University of the Western Cape, 2008)This secondary analysis aimed to develop dietary scores to assess the dietary intake of pregnant women in the West Coast/ Winelands region and determine the association with LBW. Further to determine the association between ... -
Association between antioxidant activities and drought responses of two contrasting sugar beet genotypes
(University of the Western Cape, 2017)Sugar beet (Beta vulgaris L), which belongs to the Amaranthaceae family is a biennial crop widely used as a source of domestic sugar in the European countries, United States, China and Japan. However, in South Africa, sugar ... -
AtNOGC1 protein bioelectrode for the determination of stress signalling molecules - Nitric Oxide (NO), Carbon Monoxide (CO) and Calcium ion (Ca2+)
(University of the Western Cape, 2018)It has been estimated that the world population will reach about 10 billion by the year 2050 and in order to accommodate the increased demand of food, the world agricultural production needs to rise by 70 % in the year ... -
Bacteriophage diversity in haloalkaline environments
(University of the Western Cape, 2013)There are limited reports on virus population in haloalkaline environments; therefore the aim of this study was to investigate the genetic diversity and biology of bacteriophage communities in these environments. Bacteria ...